can bladder infection cause cancer

Contents

image

“But typically, no, having UTIs doesn’t mean you have bladder cancer.” Bladder cancer is the sixth most common cancer in the U.S. It occurs when cells that make up the bladder lining begin to grow abnormally. As the abnormal cells multiply, they form a cluster called a tumor.May 14, 2021

Symptoms

 · Not typically, according to Tessa Flores, MD, Medical Director of Cancer Survivorship and Screening at Roswell Park Comprehensive Cancer Center. While a urinary tract infection (UTI) and bladder cancer can produce similar symptoms, Dr. Flores says, having frequent UTIs doesn’t mean you have bladder cancer. “There is preliminary data that there …

Causes

Bladder infections and bladder cancer have a lot in common. Bladder infections are the most common type of urinary tract infection (UTI), whereas bladder cancer is one of the most common types of cancer. Estimates suggest more than 80,000 new cases of bladder cancer will be diagnosed this year. A bladder infection is usually more annoying than serious unless it goes …

Prevention

Toxin-induced DNA damage to bladder cells Doctors say that approximately 80 percent (an overwhelming majority) of UTIs are caused by a bacteria known as Uropathogenic E. coli or UPEC. And now, a new study has shown that this bacteria is capable of producing a toxin known as colibactin, which has long been suspected of being involved in cancer.

Complications

In addition to being painful, an untreated bladder infection can potentially spread to the kidneys and cause permanent damage. A less common but more serious condition, bladder cancer occurs when cells in the bladder lining undergo abnormal changes that cause them to grow and divide very rapidly.

How does bladder cancer affect the urinary system?

 · The researchers found that bladder cancer diagnoses take longer and health outcomes are worse in men and women who have UTIs than in men with blood in the urine. The average time from initial…

Can recurrent UTI symptoms be a sign of cancer?

Blood in the urine doesn’t always mean you have bladder cancer. More often it’s caused by other things like an infection, benign (not cancer) tumors, stones in the kidney or bladder, or other benign kidney diseases. Still, it’s important to have it checked by a doctor so the cause can be found. Changes in bladder habits or symptoms of irritation

How to stop a chronic, recurring urinary tract infection?

Some cancer treatments, such as those listed below, may cause urinary and bladder problems: Radiation therapy to the pelvis (including reproductive organs, the bladder, colon and rectum) can irritate the bladder and urinary tract. These problems often start several weeks after radiation therapy begins and go away several weeks after treatment has been completed.

What are the symptoms of advanced bladder cancer?

 · Bladder cancer occurs when cells making up the bladder begin to grow and spread in an uncontrolled way, leading to the formation of a malignant tumor.

image

Can bladder infections turn into cancer?

Preliminary data appears to support a link between recurrent UTIs and increased risk of squamous cell carcinoma of the bladder. However, as squamous cell carcinoma is a rare type of bladder cancer (<5% of cases), the overall impact of this potential association would be relatively minor.

What happens if you have a bladder infection too long?

When left untreated, the infection from a UTI can actually move throughout the body—becoming very serious and even life threatening. If you do not treat a bladder infection, it may turn into a kidney infection, which can then result in a more serious infection that’s moved into the blood stream.

What are the warning signs of bladder cancer?

Bladder Cancer: Symptoms and SignsBlood or blood clots in the urine.Pain or burning sensation during urination.Frequent urination.Feeling the need to urinate many times throughout the night.Feeling the need to urinate, but not being able to pass urine.Lower back pain on 1 side of the body.

Can bladder infection be mistaken for cancer?

Bladder cancer can often be mistaken for a urinary tract infection, because many of the symptoms overlap. Patients may experience increased frequency of urination, urgency to urinate, pain with urination, or urinary incontinence.

What happens if a UTI goes untreated for months?

The main danger associated with untreated UTIs is that the infection may spread from the bladder to one or both kidneys. When bacteria attack the kidneys, they can cause damage that will permanently reduce kidney function. In people who already have kidney problems, this can raise the risk of kidney failure.

How do I know if my UTI is serious?

See a GP if you feel feverish and have pain that will not go away in your tummy, lower back or genitals. You should also see a GP if you have symptoms of a UTI that have not improved after a few days, or if you have blood in your pee. Contact a GP immediately if you think your child may have a kidney infection.

What is usually the first symptom of bladder cancer?

In most cases, blood in the urine (called hematuria) is the first sign of bladder cancer. There may be enough blood to change the color of the urine to orange, pink, or, less often, dark red.

What are the symptoms of stage 1 bladder cancer?

SymptomsBlood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test.Frequent urination.Painful urination.Back pain.

Who is at high risk for bladder cancer?

The chances of being diagnosed with bladder cancer increases with age. More than 70% of people with bladder cancer are older than 65. Gender. Men are 4 times more likely to develop bladder cancer than women, but women are more likely to die from bladder cancer than men.

Does bacteria in urine mean cancer?

“But typically, no, having UTIs doesn’t mean you have bladder cancer.” Bladder cancer is the sixth most common cancer in the U.S. It occurs when cells that make up the bladder lining begin to grow abnormally. As the abnormal cells multiply, they form a cluster called a tumor.

Can bladder cancer be detected with a urine test?

Urinalysis can help find some bladder cancers early, but it has not been shown to be useful as a routine screening test. Urine cytology: In this test, a microscope is used to look for cancer cells in urine. Urine cytology does find some cancers, but it’s not reliable enough to make a good screening test.

Does bladder cancer show up in blood tests?

Tests to diagnose bladder cancer If bladder cancer is suspected, these tests may be performed to diagnose the disease: Physical exam. Blood test: Blood samples are used to measure certain substances released into the blood by organs and tissues in the body.

image

How does bladder cancer develop?

Bladder cancer develops when cells in the bladder begin to grow abnormally, forming a tumor in the bladder. Bladder cancer begins when cells in the bladder develop changes (mutations) in their DNA. A cell’s DNA contains instructions that tell the cell what to do.

What type of cancer is a bladder cancer?

Types of bladder cancer include: Urothelial carcinoma. Urothelial carcinoma , previously called transitional cell carcinoma, occurs in the cells that line the inside of the bladder. Urothelial cells expand when your bladder is full and contract when your bladder is empty.

What is the most common type of bladder cancer?

Urothelial carcinoma is the most common type of bladder cancer in the United States. Squamous cell carcinoma. Squamous cell carcinoma is associated with chronic irritation of the bladder — for instance, from an infection or from long-term use of a urinary catheter. Squamous cell bladder cancer is rare in the United States.

What is the male urinary system?

Male urinary system. Your urinary system — which includes your kidneys, ureters, bladder and urethra — removes waste from your body through urine. Your kidneys, located in the rear portion of your upper abdomen, produce urine by filtering waste and fluid from your blood. Bladder cancer is a common type …

Why are men more likely to get bladder cancer than women?

Men are more likely to develop bladder cancer than women are. Exposure to certain chemicals. Your kidneys play a key role in filtering harmful chemicals from your bloodstream and moving them into your bladder. Because of this, it’s thought that being around certain chemicals may increase the risk of bladder cancer.

How do you know if you have bladder cancer?

Bladder cancer signs and symptoms may include: Blood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test. Frequent urination. Painful urination. Back pain.

Where does bladder cancer start?

Bladder cancer is a common type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in your lower abdomen that stores urine. Bladder cancer most often begins in the cells (urothelial cells) that line the inside of your bladder. Urothelial cells are also found in your kidneys and the tubes (ureters) …

How many people get bladder cancer every year?

About 84,000 people develop bladder cancer every year, according to the National Cancer Institute’s SEER database. That means 2.4% of people will get bladder cancer during their lives. 10

How to diagnose bladder cancer?

To diagnose bladder cancer or a bladder infection, a medical professional will start by asking you about your symptoms and your personal and family health history. They’ll likely also perform a physical exam.

What test is used to determine if a bacteria is in your bladder?

Tests would include a urinalysis to test if bacteria are in your bladder or urinary tract and if your immune system is fighting an infection. They may also use a urine culture test to determine what kind of bacteria is causing the infection. 8

What does it feel like to have a bladder infection?

The main symptom of a bladder infection is a burning feeling when you urinate. You may also feel an intense urge to urinate but then be able to let out little urine when you try to relieve yourself. 2

What does it mean when you have blood in your urine?

Blood in the urine is also a common symptom of a bladder infection , so it is one that is often misdiagnosed in women presenting with bladder cancer. 4

Where is the bladder located?

Your bladder is the organ located in the urinary tract . It is the waystation between your kidneys, which filter waste out of the bloodstream to make urine, and your urethra, which is the tube that your urine passes through when you urinate. The bladder collects urine and stores it until you’re ready to release it. 1

How is bladder cancer treated?

Bladder cancers are treated with surgery, radiation, chemotherapy, immunotherapy (including BCG ), and targeted therapy. Depending on how advanced bladder cancer is when first diagnosed, an oncologist will prescribe different treatments. Multiple types of treatments, at the same time or in succession, may be laid out in your treatment plan 5

What are the risk factors for bladder infection?

Risk factors for bladder infection include: Gender (bladder infections are more common in women) Age (lack of estrogen during menopause causes changes in the urinary tract that can lead to infection) Kidney stones or an enlarged prostate. Catheter use. Diabetes or another immune disorder.

What is the most common type of urinary tract infection?

Bladder infections are the most common type of urinary tract infection (UTI). Bladder cancer is one of the most common types of cancer. Estimates suggest more than 80,000 new cases will be diagnosed this year. A bladder infection is usually more annoying than serious, unless it goes untreated and causes complications.

Is bladder cancer more serious than bladder cancer?

A bladder infection is usually more annoying than serious, unless it goes untreated and causes complications. Bladder cancer, on the other hand, can be very serious and may even require surgery. Symptoms of a bladder infection can be very similar to those of bladder cancer, making it difficult to know which one you’re dealing with.

Is it normal to see blood in your urine?

A history of tobacco use (current or past tobacco use, along with blood in your urine is a worrisome combination) If you notice changes in your urination habits or see blood in your urine (which is not normal), it’s time to see your doctor. Even if you suspect it’s just an infection, it’s important to seek treatment.

Can a bladder infection spread to both kidneys?

Even if you suspect it’s just an infection, it’s important to seek treatment. Infection may spread from the bladder to one or both kidneys. When bacteria attack the kidneys, it can cause permanent kidney damage.

What are the symptoms of urinary tract infection?

Pain, burning, urgency — each of these symptoms will sound familiar if you’ve ever suffered from urinary tract infections. And most of us have.

What is the cause of UTIs?

Doctors say that approximately 80 percent (an overwhelming majority) of UTIs are caused by a bacteria known as Uropathogenic E. coli or UPEC. And now, a new study has shown that this bacteria is capable of producing a toxin known as colibactin, which has long been suspected of being involved in cancer.

Is there a systematic search for colibactin markers in urine?

And they conclude, “Our work suggests that there should be a more specific follow-up of patients regularly suffering from urinary tract infections , with a systematic search for colibactin markers in their urine, but also more proactive, by proposing therapeutic approaches aimed at modulating the composition of their intestinal microbiota, which represents the main reservoir of the E. coli bacteria involved in these urinary tract infections.”

What is the most common symptom of bladder cancer?

And he said that because the most common symptom of bladder cancer is blood in the urine, also called “hematuria,” UTI-like symptoms don’t always raise suspicion.

Which is more likely to have cancer at diagnosis: UTI or blood in urine?

Also, both men and women who had a UTI were more likely to have more-advanced cancer at diagnosis than men who had blood in the urine.

Is bladder cancer worse in men or women?

The researchers found that bladder cancer diagnoses take longer and health outcomes are worse in men and women who have UTIs than in men with blood in the urine. The average time from initial symptoms to bladder cancer diagnosis was longer in women than in men.

Why is bladder cancer so early?

Bladder cancer can often be found early because it causes blood in the urine or other urinary symptoms that cause a person to see a health care provider.

What are the symptoms of bladder cancer?

Being unable to urinate. Lower back pain on one side. Loss of appetite and weight loss. Feeling tired or weak. Swelling in the feet. Bone pain. Again, many of these symptoms are more likely to be caused by something other than bladder cancer, but it’s important to have them checked.

Why does urine have blood in it?

More often it’s caused by other things like an infection, benign (not cancer) tumors, stones in the kidney or bladder, or other benign kidney diseases. Still, it’s important to have it checked by a doctor so the cause can be found.

Why do I have trouble peeing?

Having to get up to urinate many times during the night. These symptoms are more likely to be caused by a urinary tract infection (UTI), bladder stones, an overactive bladder, or an enlarged prostate (in men).

How long does urine stay clear after bladder cancer?

Blood may be present one day and absent the next, with the urine remaining clear for weeks or even months. But if a person has bladder cancer, at some point the blood reappears.

Can bladder cancer cause a change in urination?

Bladder cancer can sometimes cause changes in urination, such as: Having to urinate more often than usual. Pain or burning during urination. Feeling as if you need to go right away, even when your bladder isn’t full. Having trouble urinating or having a weak urine stream.

What are some ways to make your bladder worse?

You’ll want to stay away from things that can make bladder problems worse. These include caffeine, drinks with alcohol, spicy foods, and tobacco products. Prevent urinary tract infections. Your doctor or nurse will talk with you about ways to lower your chances of getting a urinary tract infection.

How long does it take for a bladder to irritate after radiation?

Radiation therapy to the pelvis (including reproductive organs, the bladder, colon and rectum) can irritate the bladder and urinary tract. These problems often start several weeks after radiation therapy begins and go away several weeks after treatment has been completed. Some types of chemotherapy and immunotherapy can also affect …

What does radiation cystitis mean?

Irritation of the bladder lining ( radiation cystitis ): pain or a burning feeling when you urinate. blood in your urine ( hematuria) trouble starting to urinate. trouble emptying your bladder completely ( urinary retention) feeling that you need to urinate urgently or frequently. leaking a little urine when you sneeze or cough.

How do you know if you have an infection?

Let your doctor know if you feel burning or cramping or if you have any pain. Those could be signs of an infection. Tell your doctor if you feel like you have to urinate right away. And call if you feel you can’t get all the urine out or if the urine leaks from your bladder when you sneeze or cough.

What does it mean when you have a UTI?

pain in your back or abdomen. difficulty urinating or not being able to urinate. In people being treated for cancer, a UTI can turn into a serious condition that needs immediate medical care.

Is it normal for a chemo patient to have a change in their urine?

Talk with your doctor or nurse to learn what symptoms you may experience and ask which ones to call about. Some urinary or bladder changes may be normal, such as changes to the color or smell of your urine caused by some types of chemotherapy.

Do bladder problems go away after treatment?

So talk with them. There may be medicines or exercises to help with some of these problems. And the good news is that most bladder problems go away after treatment.

What causes bladder cancer?

Bladder cancer occurs when cells making up the bladder begin to grow and spread in an uncontrolled way, leading to the formation of a malignant tumor. This abnormal cell growth is caused by mutations in the genes that control cell replication, repair, and programmed death: genes that help cells to grow and divide may be switched on, whereas genes that regulate cell division, repair, and programmed death may be switched off.

Why do women have more advanced bladder cancer?

A major reason for women presenting with more advanced tumors is the delay that can occur before receiving a bladder cancer diagnosis. Reasons for this delay may include: Blood in the urine, the most common symptom of bladder cancer, may be discounted by women as being related to menstruation or post-menopausal bleeding.

How long does it take to get a urine sample from CXbladder?

Cxbladder’s unique urine sampling system is non-invasive and easy-to-use. The process is quick and painless, taking only minutes, and you can expect reliable results in seven working days. To simplify and streamline the bladder cancer testing process, we are now offering in-home sampling for patients in the US.

Why does my bladder bleed?

Blood in the urine is the most common sign of bladder cancer and is also often the first sign noticed. This is because early bladder cancer frequently causes bleeding without pain or other symptoms.

What chemicals can cause bladder cancer?

Exposure to certain chemicals in the workplace: Aromatic amines used in the dye industry and organic chemicals used in the production of rubber, leather, paint and textiles may contribute to a higher bladder cancer rates in workers. Painters, printers, hairdressers, and truck drivers are also at increased risk due to workplace exposures.

How old is the average person with bladder cancer?

Age: Bladder cancer mostly affects people >55 years of age. In the United States, the average age of individuals diagnosed with bladder cancer is 73 years.

Can a UTI be a sign of cancer?

Can Recurrent UTI Symptoms Be a Sign of Cancer? Urinary tract infections (UTIs) are much more common in women than in men, and the symptoms can be similar to bladder cancer, reinforcing the importance of an accurate diagnosis. Here we give an overview of UTIs and discuss why it is important to rule out bladder cancer if you are experiencing …

Symptoms

Causes

Medically reviewed by
Dr. Pawan Katti

Symptoms

If you or someone you know is exhibiting symptoms of Bladder cancer, seek medical attention immediately.

Symptoms include:

  • Blood in urine
  • Difficulty in urinating
  • Low back pain
  • Rapid weight loss
  • loss of appetite
  • Swollen feet
  • Extreme weakness and tiredness
Causes

  • A tumor develops when cells in the bladder grow unusually. Risk factors of bladder cancer include
  • Tobacco use
  • Smoking
  • A job involving exposure to chemicals
  • Exposure to radiation
  • Recurrent infections in the bladder
Prevention

In spite of the fact that there’s no ensured approach to prevent bladder cancer, a healthy lifestyle is recommended to minimize the risk

  • Avoid smoking
  • Consume fruits and vegetables which are rich in antioxidants
  • Adequate fluid intake to get rid of harmful chemicals that build up in the bladder
Complications

If untreated for a prolonged period it may lead to

  • Bladder cancers may spread into the close-by organs.
  • Affect pelvic lymph nodes and can spread to the liver, lungs, and bones
  • Anemia
  • Swelling of the urethras
  • Urethral stricture
  • Urinary incontinence

Diagnosis

Treatment

Prevention

Summary

A Word from Verywell

  • Bladder cancer begins when cells in the bladder develop changes (mutations) in their DNA. A cell’s DNA contains instructions that tell the cell what to do. The changes tell the cell to multiply rapidly and to go on living when healthy cells would die. The abnormal cells form a tumor that can invade and destroy normal body tissue. In time, the abnor…

See more on mayoclinic.org

Leave a Comment