does bladder cancer metastasis

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Bladder cancer can also spread to another part of the body. This is secondary cancer or metastasis. The places it’s most likely to spread to are your: lymph nodes in the pelvis and tummy (abdomen)

Can bladder cancer kill you?

Bladder cancer spreads when cancerous cells reproduce and invade surrounding healthy tissues. This is known as metastasis. Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well.

How dangerous is bladder cancer?

When bladder cancer spreads to other parts of the body When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis. Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

How quickly does bladder cancer grow and spread?

 · For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis. Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer. It’s not called bone cancer unless it starts in the bone.

How do doctors determine if bladder cancer has spread?

Metastatic pattern of bladder cancer: correlation with the characteristics of the primary tumor Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier.

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Where does bladder cancer typically metastasize?

CONCLUSION. Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier. Tumors with atypical histologic features also have a higher frequency of peritoneal metastasis.

Is bladder cancer likely to metastasize?

As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. Most patients with overt metastatic disease die within 2 years despite chemotherapy.

What percent of bladder cancer is metastatic?

Metastatic disease, which accounts for only 5% of cases in the US, has a 5-year survival under 5%. The greatest risk factor for the urothelial subtype, which comprises 90% of all cases, is tobacco smoking. Smoking accounts for 50–65% of all bladder cancer cases and increases the risk of the disease by 3-fold.

Does bladder cancer spread quickly?

They tend to grow and spread slowly. High-grade bladder cancers look less like normal bladder cells. These cancers are more likely to grow and spread.

What are the signs that bladder cancer has spread?

The signs and symptoms of bladder cancer that has spread to other parts of the body include:tiredness or weakness.pain when urinating.difficulty urinating or inability to urinate.pain in the lower back on one side of the body.weight loss.swollen feet.bone pain.

What are the symptoms of metastatic bladder cancer?

Symptoms of metastatic bladder cancerBlood in the urine.Frequent urination.Pain or burning during urination.Need to urinate despite an empty bladder.Being unable to urinate.Lower back and abdominal pain.Swelling in the feet.Fatigue and weakness.More items…•

What is the life expectancy of someone with bladder cancer?

5-year relative survival rates for bladder cancerSEER Stage5-year Relative Survival RateIn situ alone Localized96% 70%Regional38%Distant6%All SEER stages combined77%Mar 1, 2022

What are the chances of bladder cancer spreading?

About 1 in 3 bladder cancers have spread into deeper layers but are still only in the bladder. In most of the remaining cases, the cancer has spread to nearby tissues or lymph nodes outside the bladder. Rarely (in about 4% of cases), it has spread to distant parts of the body.

Can you survive metastatic bladder cancer?

Patients who present with metastatic bladder cancer generally have a poor prognosis, surviving only very few months (1). However, some patients may live considerably longer. If a patient is able to withstand palliative chemotherapy, their remaining lifetime may be extended with systemic treatments.

Can cancer come back after bladder removal?

Around 1 in 4 people are diagnosed at this stage. However, after removing the bladder, the cure rate is far from perfect. “We know that even when patients undergo surgical removal of the bladder for muscle-invasive bladder cancer, the risk of metastatic recurrence is about 50%,” said Dr.

Does bladder cancer always come back?

Bladder cancer cells can recur in the bladder or they can recur in other parts of the body. Some people who are treated for bladder cancer never have a recurrence. Although recurrence is not uncommon among people who are treated for bladder cancer, in many cases the recurrence can be treated effectively.

What bones does bladder cancer spread to?

Bone was the initial metastatic site for 25/48 patients (52.1%) and pain was the initial symptoms for 54.2% of patients. The most common locations were pelvis 64.6%, spine 58.3%, rib 20.8%, femur 12.5%, humerus 6.3% and clavicle 6.3%.

How long can you live with metastatic bladder cancer?

Patients who present with metastatic bladder cancer generally have a poor prognosis, surviving only very few months (1). However, some patients may live considerably longer. If a patient is able to withstand palliative chemotherapy, their remaining lifetime may be extended with systemic treatments.

What causes metastatic bladder cancer?

While the exact cause of bladder cancer is not known, certain risk factors are linked to the disease, including tobacco smoking and exposure to certain chemicals and gases. Also, people with a family history of bladder cancer have a high risk of developing the disease.

What is the mortality rate of bladder cancer?

5-year relative survival rates for bladder cancerSEER Stage5-year Relative Survival RateIn situ alone Localized96% 70%Regional38%Distant6%All SEER stages combined77%Mar 1, 2022

How fast does high grade bladder cancer spread?

T1Hg bladder cancer progresses to muscle-invasive or metastatic disease at a rate of 30% to 50% after 5 years. As a result, some studies advocate initial cystectomy based on the perceived acceptable morbidity and a 5-year disease-specific survival rate of 80% to 90%.

How Does The Doctor Know I Have Bladder Cancer?

Bladder cancer might cause symptoms such as: 1. Having trouble peeing 2. Feeling pain when peeing 3. Needing to go more often than normal 4. Seeing…

Tests to Look For Bladder Cancer

Your doctor may do other tests to find out more about the cancer. Some of them are:X-ray: Dye is put into a vein for a special x-ray of the kidneys…

How Serious Is My Cancer?

If you have bladder cancer, the doctor will want to find out how far it has spread. This is called staging. Your doctor will want to find out the s…

What Kind of Treatment Will I Need?

There’s more than one way to treat bladder cancer. You might want to get a second opinion about the best treatment plan for you. Doctors may have d…

What Will Happen After Treatment?

You will be glad when treatment is over. But it’s hard not to worry about cancer coming back. Even when cancer never comes back, people still worry…

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Where Bladder Cancer Can Spread

The bladder is a hollow organ that holds urine. It has flexible walls that are composed of several layers. When bladder cancer starts to spread, it grows through each layer of the bladder wall.

Symptoms and Complications

The first symptom of bladder cancer is usually blood in the urine. However, it’s possible to have blood in your urine and not see it. Laboratory testing can identify blood in urine, even when it’s not visible to the eye. As bladder cancer spreads, you may experience other symptoms, too. Advanced bladder cancer symptoms include: 5

Treatment Options

Treatments for metastatic bladder cancer can vary, based on things like how extensively your cancer has spread, your overall health and strength, and your current symptoms.

Living With Bladder Cancer

Bladder cancer symptoms and treatments can be overwhelming. No matter where you are on your treatment journey, you’ll need to meet with your healthcare provider for regular checkups and tests. Talking to your healthcare team about the next steps and what to expect can provide a road map during this time.

Prognosis

Metastatic bladder cancer is a challenging diagnosis. Your health, strength, and age will all play a role in your prognosis. How well your cancer responds to treatment is also a significant factor.

Summary

Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder.

A Word From Verywell

A diagnosis of metastatic bladder cancer can feel overwhelming, but there’s treatment to help manage symptoms and slow disease progression. No matter where you are on your treatment journey, it’s important to maintain regular appointments with your healthcare provider to keep your cancer under control.

What is metastatic bladder cancer?

Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones. Even if the cancer cells are first discovered in the bones, for example, if they first started growing in the bladder it is still called metastatic bladder cancer. 1.

What is it called when bladder cancer spreads to other parts of the body?

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis . Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

What is bladder cancer made of?

Metastatic Bladder Cancer. The bladder is a flexible, hollow organ that is mostly made of muscle, but it has a thin layer of cells lining the inside of the bladder walls called the urothelium. In most patients with bladder cancer, the cancer cells started to grow in this inner lining of the bladder. As the number of cancer cells grows, they can …

What is it called when cancer cells break away from where they started to grow and start spreading to other parts of the body

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis. Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones. Even if the cancer cells are first discovered in the bones, …

What is it called when cancer cells grow in the bladder?

Even if the cancer cells are first discovered in the bones, for example, if they first started growing in the bladder it is still called metastatic bladder cancer. 1.

What is the procedure to see the inside of the bladder?

During the procedure, a cystoscope (lighted telescope) is inserted into your bladder from the urethra so your doctor can view the inside of your bladder. If the procedure is done under anesthesia, your doctor can also take a biopsy (tissue samples) so they can examine it for signs of cancer.

Can a doctor take a biopsy of bladder?

If the procedure is done under anesthesia, your doctor can also take a biopsy (tissue samples) so they can examine it for signs of cancer. If the tests find cancer cells or tumors in the bladder, then more tests will likely be needed to find out if there are bladder cancer cells in other parts of the body. 3.

What is it called when cancer grows in the bladder?

If the cancer grows into the outer layers of the bladder, it’s called invasive. Invasive cancers are more likely to spread and can be harder to treat.

How to remove bladder cancer?

This can be done during a cystoscopy. A a cystoscope with a looped wire on the end is used to remove the tumor. When the cancer is more invasive, the cancer is removed along with part of the bladder or the entire bladder.

Where does cancer start?

Cancer can start any place in the body. Cancer that starts in the bladder is called bladder cancer. It starts when cells in the bladder grow out of control and crowd out normal cells. This makes it hard for the body to work the way it should. Cancer cells can spread to other parts of the body.

What is it called when cancer cells spread to other parts of the body?

For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis . Cancer is always named for the place where it starts.

What is it called when cancer spreads to the bone?

For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis . Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer.

What is the tube that connects the kidneys to the bladder?

Tubes called ureters connect your kidneys to the bladder. Urine flows through the ureters and into your bladder, where it’s stored. When you urinate (pee), the bladder squeezes the urine out through a tube called the urethra. Bladder cancer usually starts in the lining or inner layer of the bladder wall.

What tests are done to check for bladder cancer?

This might include a rectal exam, during which a gloved finger is put into your rectum. If you are a woman, a pelvic exam might also be done.

Can you get metastatic bladder cancer without a professional?

Metastatic bladder cancer treatment. Without a professional evaluation, it can be difficult to know if the symptoms you’re experiencing are the result of blad der cancer or something else.

Can bladder cancer spread to the liver?

The most common symptoms of bladder cancer involve urinary function, although other complications can occur if the cancer spreads. It’s not uncommon for bladder cancer to metastasize to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body.

What are the symptoms of bladder cancer?

What Are the Most Common Metastatic Bladder Cancer Symptoms? The most common symptoms of bladder cancer involve urinary function, although other complications can occur if the cancer spreads. It’s not uncommon for bladder cancer to metastasize to the lungs, liver or bones.

Can bladder cancer cause pain?

It’s not uncommon for bladder cancer to metasta size to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body. In many cases, metastatic bladder cancer also causes general complications such as fatigue and weight loss.

Can bladder cancer be diagnosed without a professional?

Without a professional evaluation, it can be difficult to know if the symptoms you’re experiencing are the result of bladder cancer or something else. While it’s important not to panic – most of these issues can be caused by other, less serious conditions – it’s also important to talk with an expert if you notice something out of the ordinary. The earlier that bladder cancer is detected, the more treatment options you’re likely to have.

What is it called when bladder cancer spreads?

1,2 Bladder cancer that has spread ( metastasized) is called metastatic bladder cancer.

How does bladder cancer spread?

It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body. It can also spread through the body’s blood vessels and form tumors in other parts of the body, …

What tests determine if bladder cancer has spread?

What Tests Determine Cancer Spread? When a patient is diagnosed with bladder cancer, healthcare providers may carry out further tests to find out if the bladder cancer cells have spread to other organs or parts of the body. 1,2 Bladder cancer that has spread ( metastasized) is called metastatic bladder cancer. …

How does a tumor spread through the lymph system?

It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body. It can also spread through the body’s blood vessels and form tumors in other parts of the body, such as the bones or lungs.

Can a retrograde pyelogram detect bladder cancer?

For example, intravenous or retrograde pyelograms are types of x-rays that use a special dye to highlight the organs of the urinary tract. This can make it possible to detect cancer that has spread to the kidneys, ureters, or other parts of the urinary tract. If healthcare providers suspect that the bladder cancer may have spread to …

Can a chest x-ray detect bladder cancer?

If healthcare providers suspect that the bladder cancer may have spread to the patient’s lungs, then a chest x-ray may be used.

What is a CT scan for bladder cancer?

To check if bladder cancer has spread, CT scans may be used to create images of the entire urinary tract (including the kidneys) as well as lymph nodes, other organs in the abdomen, and the lungs.

Can bladder cancer be cured?

The outlook for people with stage 0a (non-invasive papillary) bladder cancer is very good. These cancers can be cured with treatment. During long-term follow-up care, more superficial cancers are often found in the bladder or in other parts of the urinary system.

What is the first treatment for bladder cancer?

Chemo (with or without radiation) is typically the first treatment when bladder cancer has spread to distant parts of the body (M1). After this treatment the cancer is rechecked. If it looks like it’s gone, a boost of radiation to the bladder may be given or cystectomy might be done.

What are the factors that affect cancer treatment?

Other factors, such as the size of the tumor, how fast the cancer cells are growing (grade), and a person’s overall health and preferences, also affect treatment options.

What is stage 0 bladder cancer?

Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis or carcinoma in situ). In either case, the cancer is only in the inner lining layer of the bladder. It has not invaded (spread deeper into) the bladder wall.

Can you get a partial cystectomy for bladder cancer?

Lymph nodes near the bladder are often removed as well. If cancer is in only one part of the bladder, a partial cystectomy may be done instead. But this is possible in only a small number of patients . Radical cystectomy may be the only treatment for people who are not well enough to get chemo.

Is stage IV bladder cancer hard to treat?

These cancers have reached the pelvic or abdominal wall (T4b), may have spread to nearby lymph nodes (any N), and/or have spread to distant parts of the body (M1). Stage IV cancers are very hard to get rid of completely.

Can stage IV cancer spread to lymph nodes?

These cancers have reached the pelvic or abdominal wall (T4b), may have spread to nearby lymph nodes (any N), and/or have spread to distant parts of the body (M1). Stage IV cancers are very hard to get rid of completely.

What is the first line of treatment for metastatic bladder cancer?

Then, the physician may perform a radical cystectomy to remove cancer that has invaded beyond the bladder wall. Metastatic bladder cancer: Platinum-based chemotherapy is the first line of treatment for this type of bladder cancer.

Is bladder cancer treatable?

Thus, bladder cancer, if detected in the early stage is treatable and has higher survival rates. However, if the cancer is detected in the advanced stages, treatment becomes difficult and the survival rate is low.

How long do people with bladder cancer live?

Overall, 70 to 90 percent of people with localized bladder cancer will live for at least five years or more . The physician calculates this with the help of survival rates. Survival rates indicate the percentage of people who live with a certain type of cancer for a specific time. The physician often uses an overall five-year survival rate.

What is SEER in cancer?

The surveillance, epidemiology, and end results (SEER) stages are taken from the SEER database, maintained by the National Cancer Institute. SEER database groups cancers into localized, regional, and distant stages.

What is the difference between high grade and low grade bladder cancer?

Low-grade cancers: Less aggressive cancers have a low chance of becoming high grade and do not require aggressive treatments, such as radiation or bladder removal.

Can a doctor remove a bladder tumor?

The physician may either remove the tumor or burn them down. Next, the physician places medications inside the bladder to prevent the recurrence of cancer. High-grade superficial tumors that tend to return once or twice after treatment are severe and require surgery to remove the bladder.

What is the procedure to remove bladder cancer?

Tumors in the bladder muscle: In case of bladder cancer that has invaded the muscle wall but hasn’t spread to the lymph nodes, the physician recommends radical cystectomy. In this procedure, the physician removes the bladder, nearby lymph nodes and other nearby organs.

Where Bladder Cancer Can Spread

Symptoms and Complications

Treatment Options

Living with Bladder Cancer

Prognosis

Summary

  • Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder. There are several treatments for this disease. Chemotherapy is usually the first-line …

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