what causes bladder cancer



Smoking is the single biggest risk factor for bladder cancer. This is because tobacco contains cancer-causing (carcinogenic) chemicals. If you smoke for many years, these chemicals pass into your bloodstream and are filtered by the kidneys into your urine.


Some genes control when cells grow, divide into new cells, and die: Genes that help cells grow, divide, and stay alive are called oncogenes. Genes that normally help control cell division, repair mistakes in DNA, or cause cells to die at the right time are called tumor suppressor genes.


Learn about the risk factors for bladder cancer and what you might be able to do to help lower your risk. Bladder Cancer Causes, Risk Factors, and Prevention The American Cancer Society is here to support Ukrainian patients with cancer, caregivers, and clinicians.


What Are the Symptoms of Bladder Cancer? Blood in the urine. This is the most common symptom. Having to urinate often. Pain while urinating. Back pain. Pelvic pain.


Dec 06, 2021 · Smoking is a leading cause of cancer, including bladder cancer. In fact, smoking cigarettes, cigars, or pipes is thought to contribute to around half of all bladder cancer cases. This is because toxic chemicals from tobacco smoke pass into the bloodstream from the lungs. The blood then travels to the kidneys to be filtered.

What are the chances of getting bladder cancer?

Sep 28, 2017 · What causes bladder cancer? The exact cause of bladder cancer is unknown. It occurs when abnormal cells grow and multiply quickly and uncontrollably, and invade other tissues. Who is at risk for…

How dangerous is bladder cancer?

Apr 15, 2021 · Bladder cancer refers to the uncontrolled cell growth that begins in the bladder. This happens when an abnormal change (a mutation) in the deoxyribonucleic acid (DNA) causes the DNA to malfunction. The DNA is the one that instructs the cells when to divide, grow, or die.

What are the most common symptoms of bladder cancer?

From basic information about cancer and its causes to in-depth information on specific cancer types – including risk factors, early detection, diagnosis, and treatment options – you’ll find it here. … If you have bladder cancer or are close to someone who does, knowing what to expect can help you cope. Here you can find out all about …

What is the risk factor of bladder cancer?

2 days ago · Infection with Schistosoma haematobium (bilharzia or schistosomiasis) may cause bladder cancer, specially of the squamous cell type. Schistosoma eggs induces a chronic inflammatory state in the bladder wall resulting in tissue fibrosis. Higher levels of N-nitroso compounds has been detected in urine samples of people with schistosomiasis.

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May 05, 2022 · Possible Causes Of Bladder Cancer: Smoking. Smoking is the greatest known risk factor for bladder cancer smokers are four times more likely to get bladder cancer than nonsmokers. Harmful chemicals from cigarette smoke enter the bloodstream in the lungs and are ultimately filtered by the kidneys into the urine. This leads to a concentration of …


What are the two greatest risk factors for bladder cancer?

Risk factors you can changeSmoking. Smoking is the most important risk factor for bladder cancer. … Workplace exposures. Certain industrial chemicals have been linked with bladder cancer. … Certain medicines or herbal supplements. … Arsenic in drinking water. … Not drinking enough fluids. … Race and ethnicity. … Age. … Gender.More items…•

How do you catch bladder cancer?

Risk factorsSmoking. Smoking cigarettes, cigars or pipes may increase the risk of bladder cancer by causing harmful chemicals to accumulate in the urine. … Increasing age. … Being male. … Exposure to certain chemicals. … Previous cancer treatment. … Chronic bladder inflammation. … Personal or family history of cancer.

What type of people get bladder cancer?

Bladder cancer occurs mainly in older people. About 9 out of 10 people with this cancer are over the age of 55. The average age of people when they are diagnosed is 73. Overall, the chance men will develop this cancer during their life is about 1 in 27.

Is cancer in the bladder curable?

The stage of the cancer (whether it is superficial or invasive bladder cancer, and whether it has spread to other places in the body). Bladder cancer in the early stages can often be cured. The type of bladder cancer cells and how they look under a microscope.

What are the 5 warning signs of bladder cancer?

Here are five warning signs to watch for:Blood in the urine (hematuria). This is the most common early symptom of bladder cancer and typically the first sign of bladder cancer that is seen. … UTI-like symptoms. … Unexplained pain. … Decreased appetite. … Postmenopausal uterine bleeding.

What is usually the first symptom of bladder cancer?

In most cases, blood in the urine (called hematuria) is the first sign of bladder cancer. There may be enough blood to change the color of the urine to orange, pink, or, less often, dark red.

Does caffeine cause bladder cancer?

In summary, findings from this large meta-analysis of prospective studies suggest that coffee consumption was not significantly associated with long-term risk of bladder cancer. Such a null association was similar for men and women, and was confirmed in never smokers.

Do you feel ill with bladder cancer?

Nausea and vomiting. Burning or pain when you urinate, feeling the need to go often, or blood in urine. Diarrhea. Feeling tired.

Does alcohol cause bladder cancer?

Conclusion: No significant association between alcohol consumption and bladder cancer risk was found in the entire population, but there was a linear dose-response relation in those who consume alcohol from liquor or spirits. Alcohol may elevate the risk of bladder cancer in males in a dose-independent way.

Can u live without your bladder?

It can affect your body image, and you may worry about its impact on your relationships and sex life. With enough time, you should be able to do almost everything you did before. Even if you now use a urostomy bag (to collect your urine), you can go back to work, exercise, and swim.

How can bladder cancer be prevented?

Can Bladder Cancer Be Prevented?Don’t smoke. Smoking is thought to cause about half of all bladder cancers. … Limit exposure to certain chemicals in the workplace. Workers in industries that use certain organic chemicals have a higher risk of bladder cancer. … Drink plenty of liquids. … Eat lots of fruits and vegetables.

Are most bladder cancers caught early?

Bladder cancer can often be found early because it causes blood in the urine or other urinary symptoms that cause a person to see a health care provider. In most cases, blood in the urine (called hematuria) is the first sign of bladder cancer.


How does bladder cancer develop?

Bladder cancer develops when cells in the bladder begin to grow abnormally, forming a tumor in the bladder. Bladder cancer begins when cells in the bladder develop changes (mutations) in their DNA. A cell’s DNA contains instructions that tell the cell what to do.

Where does bladder cancer start?

Bladder cancer is a common type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in your lower abdomen that stores urine. Bladder cancer most often begins in the cells (urothelial cells) that line the inside of your bladder. Urothelial cells are also found in your kidneys and the tubes (ureters) …

Where is the bladder located?

Your kidneys, located in the rear portion of your upper abdomen, produce urine by filtering waste and fluid from your blood. Bladder cancer is a common type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in your lower abdomen that stores urine. Bladder cancer most often begins in …


Where is urothelial cancer found?

Urothelial cells are also found in your kidneys and the tubes (ureters) that connect the kidneys to the bladder. Urothelial cancer can happen in the kidneys and ureters, too, but it’s much more common in the bladder. Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable.

Can bladder cancer come back?

But even early-stage bladder cancers can come back after successful treatment. For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs.

How do you know if you have bladder cancer?

Bladder cancer signs and symptoms may include: Blood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test. Frequent urination. Painful urination. Back pain.


What is the most common type of bladder cancer?

Urothelial carcinoma is the most common type of bladder cancer in the United States. Squamous cell carcinoma. Squamous cell carcinoma is associated with chronic irritation of the bladder — for instance, from an infection or from long-term use of a urinary catheter. Squamous cell bladder cancer is rare in the United States.

Risk Factors

A risk factor is anything that affects your chance of getting a disease such as cancer. Learn more about the risk factors for bladder cancer.


There’s no way to completely prevent cancer. But there are things you can do that might help lower your risk. Learn more.


How do you know if you have bladder cancer?

What Are the Symptoms of Bladder Cancer? 1 Blood in the urine. This is the most common symptom. 2 Having to urinate often. 3 Pain while urinating. 4 Back pain. 5 Pelvic pain.

What is the data visualization tool?

The Data Visualizations tool makes it easy for anyone to explore and use the latest official federal government cancer data from United States Cancer Statistics. It includes the latest cancer data covering the U.S. population.

Where does bladder cancer occur?

Bladder cancer occurs in the tissues of the bladder, which is the organ in the body that holds urine. According to the National Institutes of Health, approximately 45,000 men and 17,000 women per year are diagnosed with the disease.


What is the most common type of bladder cancer?

Transitional cell carcinoma. Transitional cell carcinoma is the most common type of bladder cancer. It begins in the transitional cells in the inner layer of the bladder. Transitional cells are cells that change shape without becoming damaged when the tissue is stretched.

What is the name of the cancer that starts when glandular cells form in the bladder?

Adenocarcinoma. Adenocarcinoma is also a rare cancer in the United States. It begins when glandular cells form in the bladder after long-term bladder irritation and inflammation. Glandular cells are what make up the mucus-secreting glands in the body.

Can bladder cancer cause pain in the urine?

Many people with bladder cancer can have blood in their urine but no pain while urinating. There are a number of symptoms that might indicate bladder cancer like fatigue, weight loss, and bone tenderness, and these can indicate more advanced disease. You should pay particular attention to the following symptoms:


Does smoking cause bladder cancer?

Smoking increases your risk of bladder cancer. Smoking causes half of all bladder cancers in men and women. The following factors also increase your risk of developing bladder cancer: being older, since the majority of bladder cancers occur in people over the age of 55.

What is the treatment for cancer before surgery?

chemotherapy, radiation therapy, or immunotherapy that can be done to shrink the tumor before surgery, to treat the cancer when surgery isn’t an option, to kill remaining cancer cells after surgery, or to prevent the cancer from recurring.

What is the survival rate for bladder cancer?

The five-year survival rate for people with stage 2 bladder cancer is around 63 percent. The five-year survival rate for people with stage 3 bladder cancer is around 46 percent. The five-year survival rate for people with stage 4 bladder cancer is around 15 percent. There are treatments available for all stages.


Can you prevent bladder cancer?

There is no sure way to prevent bladder cancer. But you can take certain measures to lower your risk of developing it. These include the following:

Top What Is the Main Cause of Bladder Cancer? Related Articles

Bladder cancer occurs when cancerous cells, often from the lining of the bladder, begin to multiply. Find more information about bladder cancer, the stages of bladder cancer, and available treatment options.

What is bladder cancer?

Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder. Symptoms include blood in the urine, pain with urination, and low back pain. It is caused when epithelial cells that line the bladder become malignant.


What is the treatment for bladder cancer?

Treatment depends on the stage of the cancer. It may include some combination of surgery, radiation therapy, chemotherapy, or immunotherapy. Surgical options may include transurethral resection, partial or complete removal of the bladder, or urinary diversion.

Where is the highest rate of bladder cancer?

In 2018, the highest rate of bladder cancer occurred in Southern and Western Europe followed by North America with rates of 15, 13, and 12 cases per 100,000 people. The highest rates of bladder cancer deaths were seen in Northern Africa and Western Asia followed by Southern Europe.

Is blood in urine a sign of bladder cancer?

Blood in the urine is the most common symptom in bladder cancer, and is painless. Visible blood in the urine may be of only short duration, and a urine test may be required to confirm non-visible blood. Between 80 and 90% of people with bladder cancer initially presented with visible blood.


Does smoking cigarettes cause bladder cancer?

Smoking (cigar, pipe, Egyptian waterpipe and smokeless tobacco) in any form increases the risk for bladder cancer. Quitting smoking reduces the risk. Risk of bladder cancer decreases by 30% within 1–4 years and continues to decrease by 60% at 25 years after smoking cessation.

Does opium cause bladder cancer?

Opium consumption increases the risk of bladder cancer by 3-fold and concurrent use of opium and smoking increases the risk of bladder cancer by 5 times compared to the general population. Thirty percent of bladder tumors probably result from occupational exposure in the workplace to carcinogens.

Does eating vegetables help with bladder cancer?

As of 2019, there is limited high level evidence to suggest that eating vegetable and fruits decreases the risk of bladder cancer. A 2008 study concluded that “specific fruit and vegetables may act to reduce the risk of bladder cancer.” Fruit and yellow-orange vegetables, particularly carrots and those containing selenium, are probably associated with a moderately reduced risk of bladder cancer. Citrus fruits and cruciferous vegetables were also identified as having a possibly protective effect. However an analysis of 47,909 men in the Health Professionals Follow-Up Study showed little relation between cancer reduction and high consumption of fruits and vegetables overall, or yellow or green leafy vegetables specifically, compared to the reduction seen among those men who consumed large amounts of cruciferous vegetables. An inverse relation between in-takes of flavonols and lignans ( diphenolic compounds found in whole grains, legumes, fruits and vegetables) and aggressive bladder cancer has also been described.

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