what treatment for bladder cancer

Contents

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Medication

Chemo (with or without radiation) is typically the first treatment when bladder cancer has spread to distant parts of the body (M1). After this treatment the cancer is rechecked. If it looks like it’s gone, a boost of radiation to the bladder may be given or cystectomy might be done.

Procedures

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: Bladder Cancer Surgery Intravesical Therapy for Bladder Cancer Chemotherapy for Bladder Cancer Radiation Therapy for Bladder Cancer Immunotherapy for Bladder Cancer Targeted Therapy Drugs for Bladder Cancer

Therapy

The most common chemotherapeutic drug used in bladder cancer is cisplatin. Immunotherapy Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections.

Nutrition

 · Treatment of bladder cancer depends on the stage of the cancer. Treatment options include different types of surgery (transurethral resection, radical and partial cystectomy, and urinary diversion), radiation therapy, chemotherapy, and immunotherapy.

What is the best cure for bladder cancer?

In general, the main treatment options for bladder cancer are: Surgery Chemotherapy Immunotherapy (local and systemic) Targeted therapy Radiation therapy To learn more about the basics of each type of treatment, read this guide’s Types of Treatment section. Developing a …

What is the newest treatment for bladder cancer?

 · Chemotherapy drugs commonly used for bladder cancer include Mutamycin (mitomycin), Gemzar (gemcitabine), or Valstar (valrubicin). 1 Radiation therapy Immunotherapy with a drug such as Opdivo (nivolumab) System-wide chemotherapy Targeted therapy Clinical trials Summary BCG treatment is a form of immunotherapy for non-muscle invasive bladder …

What is bladder cancer, and how is it treated?

 · Drug Combinations Used in Bladder Cancer Drugs Approved for Bladder Cancer Atezolizumab Avelumab Balversa (Erdafitinib) Bavencio (Avelumab) Cisplatin Doxorubicin Hydrochloride Enfortumab Vedotin-ejfv Erdafitinib Jelmyto (Mitomycin) Keytruda (Pembrolizumab) Mitomycin Nivolumab Opdivo (Nivolumab) Padcev (Enfortumab Vedotin-ejfv) …

How do I care for someone with bladder cancer?

 · 5 common types of medication therapies to treat bladder cancer BCG intravesical immunotherapy Bacillus Calmette-Guerin (BCG) vaccination treatment is a sort of intravesical… Bacillus Calmette-Guerin (BCG) vaccination treatment is a sort of intravesical (administered directly into the bladder)… …

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 · Treatment for recurrent bladder cancer mayinclude the following: Radiation therapy as palliative therapy to relieve symptoms and …

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What is the best treatment for bladder cancer?

Transurethral resection (TURBT) is often done first to find out how far the cancer has grown into the bladder wall. Chemotherapy followed by radical cystectomy (removal of the bladder and nearby lymph nodes) is then the standard treatment.

Is bladder cancer usually curable?

The prognosis depends on the following: The stage of the cancer (whether it is superficial or invasive bladder cancer, and whether it has spread to other places in the body). Bladder cancer in the early stages can often be cured. The type of bladder cancer cells and how they look under a microscope.

Does bladder cancer spread fast?

They tend to grow and spread slowly. High-grade bladder cancers look less like normal bladder cells. These cancers are more likely to grow and spread.

What’s the latest treatment for bladder cancer?

Advanced and metastatic bladder cancer treatment A notable new FDA approval in December 2019 was enfortumab vedotin (Padcev), approved for advanced bladder cancer patients who have not responded to chemotherapy or immune checkpoint drugs.

What are the warning signs of bladder cancer?

Bladder Cancer: Symptoms and SignsBlood or blood clots in the urine.Pain or burning sensation during urination.Frequent urination.Feeling the need to urinate many times throughout the night.Feeling the need to urinate, but not being able to pass urine.Lower back pain on 1 side of the body.

What is the life expectancy of someone with bladder cancer?

5-year relative survival rates for bladder cancerSEER Stage5-year Relative Survival RateIn situ alone Localized96% 70%Regional38%Distant6%All SEER stages combined77%Mar 1, 2022

What is usually the first symptom of bladder cancer?

In most cases, blood in the urine (called hematuria) is the first sign of bladder cancer. There may be enough blood to change the color of the urine to orange, pink, or, less often, dark red.

Where is the first place bladder cancer spreads?

When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.

What are the symptoms of stage 1 bladder cancer?

SymptomsBlood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test.Frequent urination.Painful urination.Back pain.

What is the main cause of bladder cancer?

Smoking. Smoking is the single biggest risk factor for bladder cancer. This is because tobacco contains cancer-causing (carcinogenic) chemicals. If you smoke for many years, these chemicals pass into your bloodstream and are filtered by the kidneys into your urine.

Can bladder cancer be removed?

When bladder cancer is invasive, all or part of the bladder may need to be removed. This operation is called a cystectomy. Most of the time, chemotherapy is given before cystectomy is done. General anesthesia (where you are in a deep sleep) is used for either type of cystectomy.

Is bladder cancer serious?

Bladder cancer can be benign or malignant. Malignant bladder cancer may be life threatening, as it can spread quickly. Without treatment, it can damage tissues and organs. In this article, we cover everything you need to know about bladder cancer, including types, symptoms, causes, and treatments.

Can you live 10 years with bladder cancer?

Bladder cancer survival rates by stage According to the American Cancer Society , the relative survival rates for all stages of bladder cancer are: 5 years: 77 percent. 10 years: 70 percent. 15 years: 65 percent.

Is bladder cancer fatal?

It also affects females. In 2019, the American Cancer Society (ACS) predict that around 80,470 people will receive a diagnosis of bladder cancer and 17,670 will die from it in the United States. Bladder cancer can be benign or malignant. Malignant bladder cancer may be life threatening, as it can spread quickly.

What is the survival rate for stage 1 bladder cancer?

Stage 1. Around 80 out of 100 people (around 80%) survive their cancer for 5 years or more after they are diagnosed. Stage 1 means that the cancer has started to grow into the connective tissue beneath the bladder lining.

Is bladder cancer usually caught early?

Bladder cancer can often be found early because it causes blood in the urine or other urinary symptoms that cause a person to see a health care provider. In most cases, blood in the urine (called hematuria) is the first sign of bladder cancer.

Treating Stage 0 Bladder Cancer

Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis). In either case, the cancer has not inv…

Treating Stage I Bladder Cancer

Stage I bladder cancers have grown into the connective tissue layer of the bladder wall but have not reached the muscle layer.Transurethral resecti…

Treating Stage II Bladder Cancer

These cancers have invaded the muscle layer of the bladder wall. Transurethral resection (TURBT) is typically the first treatment for these cancers…

Treating Stage III Bladder Cancer

These cancers have reached the outside of the bladder and might have grown into nearby tissues or organs.Transurethral resection (TURBT) is typical…

Treating Stage IV Bladder Cancer

These cancers have reached the abdominal or pelvic wall (T4b tumors) or have spread to nearby lymph nodes or distant parts of the body. Stage IV ca…

Treating Bladder Cancer That Progresses Or Recurs

If cancer continues to grow during treatment (progresses) or comes back (recurs), your treatment options will depend on where and how much the canc…

Which Treatments Are Used For Bladder Cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: 1. Surgery 2. Intravesical th…

Which Doctors Treat Bladder Cancer?

Depending on your options, you can have different types of doctors on your treatment team. The types of doctors who treat bladder cancers include:…

Making Treatment Decisions

It’s important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decisi…

Help Getting Through Treatment

Your cancer care team will be your first source of information and support, but there are other resources for help when you need it. Hospital- or c…

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What is the treatment for bladder cancer?

Depending on the stage of the cancer and other factors, treatment options for people with bladder cancer can include: Bladder Cancer Surgery. Intravesical Therapy for Bladder Cancer. Chemotherapy for Bladder Cancer. Radiation Therapy for Bladder Cancer. Immunotherapy for Bladder Cancer. Targeted Therapy Drugs for Bladder Cancer.

Can bladder cancer be removed?

Surgery, alone or with other treatments, is used to treat most bladder cancers. Early-stage bladder tumors can often be removed. But a major concern in people with early-stage bladder cancer is that new cancers often form in other parts of the bladder over time.

What kind of doctor treats cancer?

Based on your treatment options, you might have different types of doctors on your treatment team. These doctors could include: 1 Urologists: surgeons who specialize in treating diseases of the urinary system and male reproductive system 2 Radiation oncologists: doctors who treat cancer with radiation therapy 3 Medical oncologists: doctors who treat cancer with medicines such as chemotherapy and immunotherapy

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How to decide on cancer treatment?

It’s important to discuss all of your treatment options, including their goals and possible side effects, with your doctors to help make the decision that best fits your needs. Some important things to consider include: 1 Your age and expected life span 2 Any other serious health conditions you have 3 The stage and grade of your cancer 4 The likelihood that treatment will cure your cancer (or help in some other way) 5 Your feelings about the possible side effects from treatment

What do people with cancer need?

People with cancer need support and information, no matter what stage of illness they may be in. Knowing all of your options and finding the resources you need will help you make informed decisions about your care.

What is the number to call for cancer treatment?

Call our National Cancer Information Center at 1-800-227-2345 and speak with one of our trained specialists. Palliative Care. Find Support Programs and Services in Your Area.

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Is treatment information given here official policy of the American Cancer Society?

The treatment information given here is not official policy of the American Cancer Society and is not intended as medical advice to replace the expertise and judgment of your cancer care team. It is intended to help you and your family make informed decisions, together with your doctor.

What is the treatment for bladder cancer?

Immunotherapy is a cancer treatment approach that uses drugs and vaccines to harness the immune system’s natural ability to fight cancer, in the same way it fights off infections. The approach is still being researched and there is a lot left to learn, but clinical studies have shown that immunotherapy holds a lot of promise in its ability to treat a wide range of malignancies, including some types of bladder cancer.

What is the procedure to remove a bladder tumor?

Cystectomy (Bladder Removal) Surgery. When bladder cancer tumors completely invade the bladder’s muscular wall, the standard of care is to perform bladder removal surgery. Typically, complete removal of the bladder ( radical cystectomy) is required. Partial cystectomy is rare because the requirements are that the tumor is easily accessible …

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What percentage of bladder cancer is superficial?

Bladder Cancer Liver Gallbladder and Pancreas Urological Conditions Cancer. Over 75 percent of bladder cancers remain confined to the lining of the bladder and do not invade the bladder wall. These are called nonmuscle-invasive bladder cancer, or superficial bladder cancer, and when managed well, they are associated with excellent prognoses.

What is bladder cancer?

Muscle-invasive bladder cancer, or advanced bladder cancer, is cancer that has invaded the bladder wall or spread outside of the bladder. These cancers require more aggressive clinical management. Bladder cancer treatment options vary depending on whether the cancer is nonmuscle-invasive or muscle-invasive, and specific treatments are determined …

What is the procedure called when a camera is passed through the urethra?

Cystoscopy is an outpatient procedure during which a thin, lighted tube with a camera is passed through the urethra into the bladder, allowing your doctor to see the inside of the bladder.

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What is a cystoscope?

Cystoscopy is an outpatient procedure during which a thin, lighted tube with a camera is passed through the urethra into the bladder, allowing your doctor to see the inside of the bladder. Most modern cystoscopes are also equipped with channels that permit small instruments to be passed into the bladder.

What is TUR in medical terms?

Transurethral resection (TUR) is an endoscopic or scope procedure that does not involve making an incision in the body.

What is the treatment for stage IV bladder cancer?

Treatment of stage IV bladder cancer that has spread to other parts of the body, such as the lung, bone, or liver, may include the following: Chemotherapy with or without local treatment ( surgery or radiation therapy ). Immunotherapy ( immune checkpoint inhibitor therapy ).

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What is bladder cancer?

Bladder cancer is a disease in which malignant (cancer) cells form in the tissues of the bladder. The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller to store urine made by the kidneys.

Does smoking cause bladder cancer?

Smoking can affect the risk of bladder cancer. Signs and symptoms of bladder cancer include blood in the urine and pain during urination. Tests that examine the urine and bladder are used to help diagnose bladder cancer. Certain factors affect prognosis (chance of recovery) and treatment options.

Where is the bladder located?

The bladder is a hollow organ in the lower part of the abdomen. It is shaped like a small balloon and has a muscular wall that allows it to get larger or smaller to store urine made by the kidneys. There are two kidneys, one on each side of the backbone, above the waist.

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Where does bladder cancer start?

Most bladder cancers begin in the transitional cells. Transitional cell carcinoma can be low- grade or high-grade: Low-grade transitional cell carcinoma often recurs (comes back) after treatment, but rarely spreads into the muscle layer of the bladder or to other parts of the body.

What is it called when you have cancer in your bladder?

Cancer that is in the lining of the bladder is called superficial bladder cancer. Cancer that has spread through the lining of the bladder and invades the muscle wall of the bladder or has spread to nearby organs and lymph nodes is called invasive bladder cancer. See the following PDQ summaries for more information:

What happens after bladder cancer diagnosis?

After bladder cancer has been diagnosed, tests are done to find out if cancer cells have spread within the bladder or to other parts of the body.

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Can bladder cancer recur after treatment?

Bladder cancer may recur, even after successful treatment. Because of this, people with bladder cancer need follow-up testing for years after successful treatment. What tests you’ll have and how often depends on your type of bladder cancer and how it was treated, among other factors.

How does radiation therapy help bladder cancer?

Radiation therapy. Radiation therapy uses beams of powerful energy, such as X-rays and protons, to destroy the cancer cells. Radiation therapy for bladder cancer usually is delivered from a machine that moves around your body, directing the energy beams to precise points.

How to diagnose bladder cancer?

Tests and procedures used to diagnose bladder cancer may include: Using a scope to examine the inside of your bladder (cystoscopy). To perform cystoscopy, your doctor inserts a small , narrow tube (cystoscope) through your urethra. The cystoscope has a lens that allows your doctor to see the inside of your urethra and bladder, …

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Can TURBT be used for bladder cancer?

TURBT can also be used to treat bladder cancer. Examining a urine sample (urine cytology). A sample of your urine is analyzed under a microscope to check for cancer cells in a procedure called urine cytology. Imaging tests.

What tests can be done to determine if you have bladder cancer?

Tests may include: CT scan.

What is a low grade bladder cancer?

Low-grade bladder cancer. This type of cancer has cells that are closer in appearance and organization to normal cells (well differentiated). A low-grade tumor usually grows more slowly and is less likely to invade the muscular wall of the bladder than is a high-grade tumor. High-grade bladder cancer.

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What is the best treatment for cancer?

Radiation therapy, to destroy cancer cells, often as a primary treatment when surgery isn’t an option or isn’t desired. Immunotherapy, to trigger the body’s immune system to fight cancer cells, either in the bladder or throughout the body. Targeted therapy, to treat advanced cancer when other treatments haven’t helped.

What is the best treatment for bladder cancer?

In general, the main treatment options for bladder cancer are: Surgery. Chemotherapy. Immunotherapy (local and systemic) Targeted therapy. Radiation therapy. To learn more about the basics of each type of treatment, read this guide’s Types of Treatment section.

Is bladder cancer recurrent?

This will then be followed with long-term surveillance. People with high-grade, non-muscle-invasive bladder cancer are at higher risk for the tumor returning, called a recurrent tumor. Sometimes a tumor comes back at a more advanced stage, with a risk of developing into metastatic bladder cancer.

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What is a multidisciplinary team in cancer?

In cancer care, different types of doctors often work together to create a patient’s overall treatment plan that combines different types of treatments. This is called a multidisciplinary team . This team is usually led by a urologist, a doctor who specializes in the genitourinary tract, or a urologic oncologist, a doctor who specializes in treating cancers of the genitourinary tract. Cancer care teams include a variety of other health care professionals, such as physician assistants, nurse practitioners, oncology nurses, social workers, pharmacists, counselors, dietitians, and others.

What is the first line of treatment for urothelial cancer?

The first treatment a person is given for advanced urothelial cancer is called first-line therapy . If that treatment stops working, then a person receives second-line therapy.

Can bladder cancer come back?

People with high-grade, non-muscle-invasive bladder cancer are at higher risk for the tumor returning, called a recurrent tumor. Sometimes a tumor comes back at a more advanced stage, with a risk of developing into metastatic bladder cancer.

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What is stage IV bladder cancer?

Metastatic urothelial cancer (stage IV) If bladder cancer has spread to another part of the body, doctors call it metastatic bladder cancer. If this happens, it is a good idea to talk with doctors, usually medical oncologists, who have experience in treating it.

What is it called when bladder cancer spreads?

If bladder cancer has spread to another part of the body, doctors call it metastatic bladder cancer. If this happens, it is a good idea to talk with doctors, usually medical oncologists, who have experience in treating it. Doctors can have different opinions about the best standard treatment plan.

Diagnosis

Treatment

Clinical Trials

Coping and Support

Medically reviewed by
Dr. Pawan Katti

Your provider will work with you to develop a care plan that may include one or more of these treatment options.

Treatments include surgery, chemotherapy, and biological therapy.

Medication

Immunotherapy: This therapy helps boost your immune system fight against the cancerous cells.

Atezolizumab . Durvalumab . Avelumab

Chemotherapy: Injection of cancer-fighting medications into the bladder through a catheter to kill the harmful cells.

Gemcitabine/Cisplatin . Methotrexate/ Vinblastine/Doxorubicin/Cisplatin (called MVAC) . Cisplatin/ Methotrexate/Vinblastine (called CMV) . Carboplatin/Paclitaxel . Docetaxel

Procedures

Transurethral resection of bladder tumor (TURBT): An instrument called a resectoscope is inserted into the bladder through the urethra which is used to remove abnormal tissues or tumors.

Cystectomy: Removal of a part of bladder is called as partial cystectomy or complete bladder removal which is called as radical cystectomy.

Therapy

Radiation therapy:High-energy radiation is used to kill the cancer cells.

Nutrition

Foods to eat:

  • Focus on starchy carbohydrates such as bread, pasta, rice or potatoes
  • Whole grains are highly recommended
  • Eat a variety of fruit and vegetables daily
  • Include lean protein such as meat, fish, eggs, beans or pulses
  • Have milk and cheese

Foods to avoid:

  • Eggs, total fat, butter
  • Soft drinks, caffeine, chlorinated surface water, sugar

Specialist to consult

Urologist

Specializes in the urinary tract disease.

Oncologist

Specializes in the diagnosis and treatment of cancer.

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