where does bladder cancer metastasis to

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Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well. Local bladder cancer metastasis When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers.

Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer.

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How dangerous is bladder cancer?

Once bladder cancer has reached the lymph nodes, it can travel to distant parts of the body through the lymphatic system. Separately, it can also continue to grow into surrounding areas such as the abdominal wall (peritoneum). Distant bladder cancer metastasis. Once cancerous cells have reached the lymphatic system, they can make their way to almost any part of the …

What is the treatment for Stage 3 bladder cancer?

 · For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis. Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer. It’s not called bone cancer unless it starts in the bone.

How quickly does bladder cancer grow and spread?

When bladder cancer spreads to other parts of the body When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis. Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

How do doctors determine if bladder cancer has spread?

Metastatic pattern of bladder cancer: correlation with the characteristics of the primary tumor. Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier.

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Where does bladder cancer first spread to?

When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.

What are the signs that bladder cancer has spread?

The signs and symptoms of bladder cancer that has spread to other parts of the body include:tiredness or weakness.pain when urinating.difficulty urinating or inability to urinate.pain in the lower back on one side of the body.weight loss.swollen feet.bone pain.

How quickly does bladder cancer metastasize?

As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. Most patients with overt metastatic disease die within 2 years despite chemotherapy.

What are the chances of bladder cancer spreading?

Extent of cancer at the time of diagnosis About 1 in 3 bladder cancers have spread into deeper layers but are still only in the bladder. In most of the remaining cases, the cancer has spread to nearby tissues or lymph nodes outside the bladder. Rarely (in about 4% of cases), it has spread to distant parts of the body.

When does bladder cancer spread to the liver?

What happens if bladder cancer spreads to the liver? If bladder cancer spreads to the liver, it can make it difficult for the liver to produce bile, break down fat cells and filter toxic substances out of the body. This can lead to jaundice, discolored urine and abdominal pain and swelling.

How long can you live with metastatic bladder cancer?

Patients who present with metastatic bladder cancer generally have a poor prognosis, surviving only very few months (1). However, some patients may live considerably longer. If a patient is able to withstand palliative chemotherapy, their remaining lifetime may be extended with systemic treatments.

Does bladder cancer spread to the colon?

The common sites of metastasis from a urinary bladder carcinoma include lymph nodes, bones, lung, liver, and peritoneum. Only a few cases of small bowel metastasis from urinary bladder malignancy have been reported in the English literature. Only one of these cases presented with bowel intussusception.

Can bladder cancer spread to the pancreas?

Bladder cancer usually metastasizes to lymph node, bone, and liver but metastasis to pancreas is very rare. We present a rare case of metastatic bladder carcinoma to Pancreas which was successfully managed with biliary stent placement.

Does bladder cancer spread to the brain?

Bladder cancer is known to metastasize to multiple sites of the body but rarely to the brain. When it does metastasize to the brain the prognosis is poor with median survival of 2-4 months despite treatment [8,9].

What is the life expectancy of someone with bladder cancer?

5-year relative survival rates for bladder cancerSEER Stage5-year Relative Survival RateIn situ alone Localized96% 70%Regional38%Distant6%All SEER stages combined77%Mar 1, 2022

What happens to your body when you have bladder cancer?

Bladder cancer can sometimes cause changes in urination, such as: Having to urinate more often than usual. Pain or burning during urination. Feeling as if you need to go right away, even when your bladder isn’t full.

Is a 5 cm bladder tumor large?

CONCLUSIONS: Larger tumor size (>5 cm) is associated with greater length of stay, reoperation, readmission, and death following TURBT. Patients should be counseled appropriately and likely warrant vigilant observation prior to and following hospital discharge.

How Does The Doctor Know I Have Bladder Cancer?

Bladder cancer might cause symptoms such as: 1. Having trouble peeing 2. Feeling pain when peeing 3. Needing to go more often than normal 4. Seeing…

Tests to Look For Bladder Cancer

Your doctor may do other tests to find out more about the cancer. Some of them are:X-ray: Dye is put into a vein for a special x-ray of the kidneys…

How Serious Is My Cancer?

If you have bladder cancer, the doctor will want to find out how far it has spread. This is called staging. Your doctor will want to find out the s…

What Kind of Treatment Will I Need?

There’s more than one way to treat bladder cancer. You might want to get a second opinion about the best treatment plan for you. Doctors may have d…

What Will Happen After Treatment?

You will be glad when treatment is over. But it’s hard not to worry about cancer coming back. Even when cancer never comes back, people still worry…

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Where Bladder Cancer Can Spread

The bladder is a hollow organ that holds urine. It has flexible walls that are composed of several layers. When bladder cancer starts to spread, it grows through each layer of the bladder wall.

Symptoms and Complications

The first symptom of bladder cancer is usually blood in the urine. However, it’s possible to have blood in your urine and not see it. Laboratory testing can identify blood in urine, even when it’s not visible to the eye. As bladder cancer spreads, you may experience other symptoms, too. Advanced bladder cancer symptoms include: 5

Treatment Options

Treatments for metastatic bladder cancer can vary, based on things like how extensively your cancer has spread, your overall health and strength, and your current symptoms.

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Living With Bladder Cancer

Bladder cancer symptoms and treatments can be overwhelming. No matter where you are on your treatment journey, you’ll need to meet with your healthcare provider for regular checkups and tests. Talking to your healthcare team about the next steps and what to expect can provide a road map during this time.

Prognosis

Metastatic bladder cancer is a challenging diagnosis. Your health, strength, and age will all play a role in your prognosis. How well your cancer responds to treatment is also a significant factor.

Summary

Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder.

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A Word From Verywell

A diagnosis of metastatic bladder cancer can feel overwhelming, but there’s treatment to help manage symptoms and slow disease progression. No matter where you are on your treatment journey, it’s important to maintain regular appointments with your healthcare provider to keep your cancer under control.

Where is the bladder located?

The bladder is a hollow organ that stores urine before it leaves your body. It sits in the lowest part of your belly, called your pelvis. Urine is made in your kidneys. Tubes called ureters connect your kidneys to the bladder. Urine flows through the ureters and into your bladder, where it’s stored. When you urinate (pee), the bladder squeezes the urine out through a tube called the urethra.

How do you know if you have bladder cancer?

Signs of bladder cancer are problems peeing, pain when peeing, needing to go more often than normal, and seeing blood in your urine

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What is the blue light on a cystoscopy?

Blue light cystoscopy: Sometimes, special drugs are put into the bladder during the exam. Cancer cells soak up these drugs and then glow when the doctor shines a blue light through the scope. This can help the doctor see cancer cells that might have been missed with the normal light.

What is the best test to find out if you have bladder cancer?

Ultrasound: This test uses sound waves to make pictures of the organs inside your body, like your bladder and kidneys. It can help show the size of a bladder cancer and if it has spread. Bone scan: A bone scan can help show if bladder cancer has spread to the bones. This test is not done unless you have bone pain.

What tests are done to check for bladder cancer?

This might include a rectal exam, during which a gloved finger is put into your rectum. If you are a woman, a pelvic exam might also be done.

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Where does urine go when you pee?

Urine flows through the ureters and into your bladder, where it’s stored. When you urinate (pee), the bladder squeezes the urine out through a tube called the urethra. Bladder cancer usually starts in the lining or inner layer of the bladder wall.

What is it called when cancer cells spread to other parts of the body?

For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis . Cancer is always named for the place where it starts.

What is it called when bladder cancer spreads to other parts of the body?

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis . Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

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How to treat metastatic bladder cancer?

Treatment for metastatic bladder cancer may involve a combination of chemotherapy treatments with or without surgery or radiation. Systemic chemotherapy is typically used as first-line treatment for metastatic bladder cancer, but this can vary for each person. Systemic means the chemotherapy drugs target the cancer cells, but all of the cells in your body are also exposed to the medicine. These drugs help stop or reduce the growth of cancer cells throughout the body. 1,5

What is it called when cancer cells grow in the bladder?

Even if the cancer cells are first discovered in the bones, for example, if they first started growing in the bladder it is still called metastatic bladder cancer. 1.

How to diagnose bladder cancer?

A cystoscopy is the main test used to identify and diagnose bladder cancer. During the procedure, a cystoscope (lighted telescope) is inserted into your bladder from the urethra so your doctor can view the inside of your bladder. If the procedure is done under anesthesia, your doctor can also take a biopsy (tissue samples) so they can examine it for signs of cancer. If the tests find cancer cells or tumors in the bladder, then more tests will likely be needed to find out if there are bladder cancer cells in other parts of the body. 3

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What is systemic chemotherapy?

Systemic means the chemotherapy drugs target the cancer cells, but all of the cells in your body are also exposed to the medicine. These drugs help stop or reduce the growth of cancer cells throughout the body. 1,5. A combination of chemotherapy drugs usually works better than 1 drug alone.

What is bladder cancer made of?

Metastatic Bladder Cancer. The bladder is a flexible, hollow organ that is mostly made of muscle, but it has a thin layer of cells lining the inside of the bladder walls called the urothelium. In most patients with bladder cancer, the cancer cells started to grow in this inner lining of the bladder. As the number of cancer cells grows, they can …

How long does bladder cancer last?

The 5-year relative survival rates for people with distant bladder cancer, meaning the cancer has spread to distant parts of the body such as the lungs, liver, or bones, is about 5 percent. This means that people with metastatic bladder cancer are, on average, about 5 percent as likely as people who do not have this form …

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What are the symptoms of bladder cancer?

What Are the Most Common Metastatic Bladder Cancer Symptoms? The most common symptoms of bladder cancer involve urinary function, although other complications can occur if the cancer spreads. It’s not uncommon for bladder cancer to metastasize to the lungs, liver or bones.

Can cancer spread to bones?

Cancer that spreads to bones can weaken the bones and make them more prone to breakage . Bone metastases can also be painful, especially at night and during activity.

Can bladder cancer be diagnosed without a professional?

Without a professional evaluation, it can be difficult to know if the symptoms you’re experiencing are the result of bladder cancer or something else. While it’s important not to panic – most of these issues can be caused by other, less serious conditions – it’s also important to talk with an expert if you notice something out of the ordinary. The earlier that bladder cancer is detected, the more treatment options you’re likely to have.

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Can bladder cancer cause pain?

It’s not uncommon for bladder cancer to metasta size to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body. In many cases, metastatic bladder cancer also causes general complications such as fatigue and weight loss.

How does bladder cancer spread?

It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body. It can also spread through the body’s blood vessels and form tumors in other parts of the body, …

What tests determine if bladder cancer has spread?

What Tests Determine Cancer Spread? When a patient is diagnosed with bladder cancer, healthcare providers may carry out further tests to find out if the bladder cancer cells have spread to other organs or parts of the body. 1,2 Bladder cancer that has spread ( metastasized) is called metastatic bladder cancer. …

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Can a retrograde pyelogram detect bladder cancer?

For example, intravenous or retrograde pyelograms are types of x-rays that use a special dye to highlight the organs of the urinary tract. This can make it possible to detect cancer that has spread to the kidneys, ureters, or other parts of the urinary tract. If healthcare providers suspect that the bladder cancer may have spread to …

Where Bladder Cancer Can Spread

Symptoms and Complications

Treatment Options

Living with Bladder Cancer

Prognosis

Summary

  • Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder. There are several treatments for this disease. Chemotherapy is usually the first-line …

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