where does bladder cancer typically metastasize to

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Metastatic patterns of bladder cancer. Metastasis occurs hematogenously to all organs, most frequently the lungs, liver, bone, or lymphatically to regional lymph nodes in the pelvis, or further to retroperitoneal lymph nodes.

CONCLUSION. Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier. Tumors with atypical histologic features also have a higher frequency of peritoneal metastasis.

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Answer

How dangerous is bladder cancer?

However, the most common sites for distant bladder cancer metastases include the: Lungs. Bones. Liver. Metastatic bladder cancer can also spread to other organs in the urinary and reproductive tracts, such as the prostate, uterus and vagina.

What are the chances of dying from bladder cancer?

 · Where does bladder cancer usually metastasize to? Lymph nodes, bones, lung, liver, and peritoneum are the most common sites of metastasis from bladder cancer. Tumors in a more advanced T category and those with atypical histologic features metastasize earlier.

What is the survival rate for Stage 3 bladder cancer?

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis. Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

What is the recovery time for bladder cancer surgery?

 · For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis. Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer. It’s not called bone cancer unless it starts in the bone.

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Where does bladder cancer spread first?

When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.

Where does bladder cancer most often spread?

Not all bladder cancers will spread. But If it does it’s most likely to spread to the structures close to the bladder, such as the ureters, urethra, prostate, vagina, or into the pelvis.

Is bladder cancer likely to metastasize?

As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. Most patients with overt metastatic disease die within 2 years despite chemotherapy.

What are the signs that bladder cancer has spread?

The signs and symptoms of bladder cancer that has spread to other parts of the body include:tiredness or weakness.pain when urinating.difficulty urinating or inability to urinate.pain in the lower back on one side of the body.weight loss.swollen feet.bone pain.

What bones does bladder cancer spread to?

Bone was the initial metastatic site for 25/48 patients (52.1%) and pain was the initial symptoms for 54.2% of patients. The most common locations were pelvis 64.6%, spine 58.3%, rib 20.8%, femur 12.5%, humerus 6.3% and clavicle 6.3%.

How fast does high grade bladder cancer spread?

T1Hg bladder cancer progresses to muscle-invasive or metastatic disease at a rate of 30% to 50% after 5 years. As a result, some studies advocate initial cystectomy based on the perceived acceptable morbidity and a 5-year disease-specific survival rate of 80% to 90%.

Does bladder cancer spread to liver?

It’s not uncommon for bladder cancer to metastasize to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body. In many cases, metastatic bladder cancer also causes general complications such as fatigue and weight loss.

Does bladder cancer spread to colon?

The common sites of metastasis from a urinary bladder carcinoma include lymph nodes, bones, lung, liver, and peritoneum. Only a few cases of small bowel metastasis from urinary bladder malignancy have been reported in the English literature. Only one of these cases presented with bowel intussusception.

How long can you live with metastatic bladder cancer?

Patients who present with metastatic bladder cancer generally have a poor prognosis, surviving only very few months (1). However, some patients may live considerably longer. If a patient is able to withstand palliative chemotherapy, their remaining lifetime may be extended with systemic treatments.

What are the chances of bladder cancer spreading?

Extent of cancer at the time of diagnosis About 1 in 3 bladder cancers have spread into deeper layers but are still only in the bladder. In most of the remaining cases, the cancer has spread to nearby tissues or lymph nodes outside the bladder. Rarely (in about 4% of cases), it has spread to distant parts of the body.

What are the 5 warning signs of bladder cancer?

Here are five warning signs to watch for:Blood in the urine (hematuria). This is the most common early symptom of bladder cancer and typically the first sign of bladder cancer that is seen. … UTI-like symptoms. … Unexplained pain. … Decreased appetite. … Postmenopausal uterine bleeding.

Is a 5 cm bladder tumor large?

CONCLUSIONS: Larger tumor size (>5 cm) is associated with greater length of stay, reoperation, readmission, and death following TURBT. Patients should be counseled appropriately and likely warrant vigilant observation prior to and following hospital discharge.

How common is it for bladder cancer to spread?

Rarely (in about 4% of cases), it has spread to distant parts of the body. Black patients are slightly more likely to have more advanced disease when they’re diagnosed, compared to whites. Survival statistics are discussed in Survival Rates for Bladder Cancer.

When does bladder cancer spread to the lungs?

It’s not uncommon for bladder cancer to metastasize to the lungs, liver or bones. This can cause pain and other symptoms in distant parts of the body. In many cases, metastatic bladder cancer also causes general complications such as fatigue and weight loss.

What are the symptoms of late stage bladder cancer?

Symptoms of advanced bladder cancerBeing unable to urinate.Lower back pain on one side.Loss of appetite and weight loss.Feeling tired or weak.Swelling in the feet.Bone pain.

Which of the following is usually the first symptom of bladder cancer?

For most people, the first symptom of bladder cancer is blood in the urine, also called hematuria. Sometimes the blood is visible, prompting the patient to visit a doctor.

How Does The Doctor Know I Have Bladder Cancer?

Bladder cancer might cause symptoms such as: 1. Having trouble peeing 2. Feeling pain when peeing 3. Needing to go more often than normal 4. Seeing…

Tests to Look For Bladder Cancer

Your doctor may do other tests to find out more about the cancer. Some of them are:X-ray: Dye is put into a vein for a special x-ray of the kidneys…

How Serious Is My Cancer?

If you have bladder cancer, the doctor will want to find out how far it has spread. This is called staging. Your doctor will want to find out the s…

What Kind of Treatment Will I Need?

There’s more than one way to treat bladder cancer. You might want to get a second opinion about the best treatment plan for you. Doctors may have d…

What Will Happen After Treatment?

You will be glad when treatment is over. But it’s hard not to worry about cancer coming back. Even when cancer never comes back, people still worry…

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Where Bladder Cancer Can Spread

The bladder is a hollow organ that holds urine. It has flexible walls that are composed of several layers. When bladder cancer starts to spread, it grows through each layer of the bladder wall.

Symptoms and Complications

The first symptom of bladder cancer is usually blood in the urine. However, it’s possible to have blood in your urine and not see it. Laboratory testing can identify blood in urine, even when it’s not visible to the eye. As bladder cancer spreads, you may experience other symptoms, too. Advanced bladder cancer symptoms include: 5

Treatment Options

Treatments for metastatic bladder cancer can vary, based on things like how extensively your cancer has spread, your overall health and strength, and your current symptoms.

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Living With Bladder Cancer

Bladder cancer symptoms and treatments can be overwhelming. No matter where you are on your treatment journey, you’ll need to meet with your healthcare provider for regular checkups and tests. Talking to your healthcare team about the next steps and what to expect can provide a road map during this time.

Prognosis

Metastatic bladder cancer is a challenging diagnosis. Your health, strength, and age will all play a role in your prognosis. How well your cancer responds to treatment is also a significant factor.

Summary

Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder.

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A Word From Verywell

A diagnosis of metastatic bladder cancer can feel overwhelming, but there’s treatment to help manage symptoms and slow disease progression. No matter where you are on your treatment journey, it’s important to maintain regular appointments with your healthcare provider to keep your cancer under control.

What is metastatic bladder cancer?

Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones. Even if the cancer cells are first discovered in the bones, for example, if they first started growing in the bladder it is still called metastatic bladder cancer. 1.

What is it called when bladder cancer spreads to other parts of the body?

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis . Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones.

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What is bladder cancer made of?

Metastatic Bladder Cancer. The bladder is a flexible, hollow organ that is mostly made of muscle, but it has a thin layer of cells lining the inside of the bladder walls called the urothelium. In most patients with bladder cancer, the cancer cells started to grow in this inner lining of the bladder. As the number of cancer cells grows, they can …

What is it called when cancer cells break away from where they started to grow and start spreading to other parts of the body

When cancer cells break away from where they started to grow and start spreading to other parts of the body, it is called metastasis. Metastatic bladder cancer is the name for bladder cancer that has spread to other parts of the body, such as the lungs, the liver, or the bones. Even if the cancer cells are first discovered in the bones, …

What is it called when cancer cells grow in the bladder?

Even if the cancer cells are first discovered in the bones, for example, if they first started growing in the bladder it is still called metastatic bladder cancer. 1.

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What is the procedure to see the inside of the bladder?

During the procedure, a cystoscope (lighted telescope) is inserted into your bladder from the urethra so your doctor can view the inside of your bladder. If the procedure is done under anesthesia, your doctor can also take a biopsy (tissue samples) so they can examine it for signs of cancer.

Can a doctor take a biopsy of bladder?

If the procedure is done under anesthesia, your doctor can also take a biopsy (tissue samples) so they can examine it for signs of cancer. If the tests find cancer cells or tumors in the bladder, then more tests will likely be needed to find out if there are bladder cancer cells in other parts of the body. 3.

What is it called when cancer grows in the bladder?

If the cancer grows into the outer layers of the bladder, it’s called invasive. Invasive cancers are more likely to spread and can be harder to treat.

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How to remove bladder cancer?

This can be done during a cystoscopy. A a cystoscope with a looped wire on the end is used to remove the tumor. When the cancer is more invasive, the cancer is removed along with part of the bladder or the entire bladder.

Where does cancer start?

Cancer can start any place in the body. Cancer that starts in the bladder is called bladder cancer. It starts when cells in the bladder grow out of control and crowd out normal cells. This makes it hard for the body to work the way it should. Cancer cells can spread to other parts of the body.

What is it called when cancer cells spread to other parts of the body?

For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis . Cancer is always named for the place where it starts.

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What is it called when cancer spreads to the bone?

For instance, cancer cells in the bladder can travel to the bone and grow there. When cancer cells spread, it’s called metastasis . Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer.

What is the tube that connects the kidneys to the bladder?

Tubes called ureters connect your kidneys to the bladder. Urine flows through the ureters and into your bladder, where it’s stored. When you urinate (pee), the bladder squeezes the urine out through a tube called the urethra. Bladder cancer usually starts in the lining or inner layer of the bladder wall.

What tests are done to check for bladder cancer?

This might include a rectal exam, during which a gloved finger is put into your rectum. If you are a woman, a pelvic exam might also be done.

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Can bladder cancer show up in kidneys?

There are lots of lesions which show up on lungs which prove not to be malignant, but yes, bladder cancer can also show up there. Try not to worry too much or get ahead of yourself. If it is limited to the kidney, there is much which can be done….#N#Hoping this all turns out well for you,#N#Karen

Is uro tumor metastatic or non-metastatic?

But if the new tumor is muscle invasive it can be considered as metastatic. Metastatic cells have more mutations than non-metastatic and these additional mutations give them the ability to dislodge from urothelium (loss of adhesion) and move. Muscle invasive tumors in the urothelium have the ability to move. This is the major event, the transition from non-invasive cells to invasive. This transformation is called Epithelial-Mesenchymal transition. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689101/#N#This process happens in many normal biological events like embrionic development and wound healing, but cancer hijacked it for metastasis.

Is a tumor in the uro tract invasive?

My understanding is that if the new tumor in the uro tract is not muscle invasive then it can be considered as a recurrence. But if the new tumor is muscle invasive it can be considered as metastatic. Metastatic cells have more mutations than non-metastatic and these additional mutations give them the ability to dislodge from urothelium (loss of adhesion) and move. Muscle invasive tumors in the urothelium have the ability to move. This is the major event, the transition from non-invasive cells to invasive. This transformation is called Epithelial-Mesenchymal transition. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2689101/#N#This process happens in many normal biological events like embrionic development and wound healing, but cancer hijacked it for metastasis.

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Can kidney cancer recur?

Yes, recurrence, from what I understand, is easier to treat than metastasis, because it can sometimes be treated locally. Yes, the prognosis is somewhat better especially if it can be treated effectively. It would be unusual to have the cancer recur in both kidneys at once, so your oncologist may be correct in her assessment. It will be crucial to monitor your dad’s kidneys and see if the spots are gone at the next CT scan date. Six weeks is a reasonable time frame prior to biopsy. It sounds like you are getting good medical advice.#N#Maja, hang in there and know that this, too, shall pass (my mother’s favorite expression). In six weeks, you’ll have more answers, and even if there is a biopsy, it may come back as some oddity, not cancer at all.#N#On the home page for BCAN, I believe there is a link to clinical trials; most are being done with metastatic cancer, but there are some (in certain NCI locations) for T1G3 cancer of the bladder, and there may be some for TCC of the kidney. Your oncologist may know of some as well, but she isn’t “jumping the gun” until she has more answers.#N#I will keep you both in my thoughts and prayers.#N#Karen

Treatments To Control Advanced Prostate Cancer

If youve just been diagnosed with advanced prostate cancer, you may be offered the following treatments:

Side Effects Of Prostate Surgery

The major possible side effects of radical prostatectomy are urinary incontinence and erectile dysfunction . These side effects can also occur with other forms of prostate cancer treatment.

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How Is Prostate Cancer Diagnosed

If you have symptoms of prostate cancer, your provider will perform a digital rectal exam and a PSA blood test. If either of those two tests are abnormal, then most likely your provider will recommend that you have a prostate biopsy.

What Questions Should I Ask My Healthcare Provider

If you have prostate cancer, you may want to ask your healthcare provider:

Receiving Treatment For Prostate Cancer That Has Spread

At Moffitt Cancer Center, the experts within our Urologic Oncology Program treat patients with all stages of prostate cancer, including advanced-stage cancers that have metastasized to other areas of the body. Our multispecialty team collaborates as a tumor board, ensuring each patient receives a treatment plan tailored to his unique needs.

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How Will My Cancer Be Monitored

Your doctor will talk to you about how often you should have check-ups. At some hospitals, you may not have many appointments at the hospital itself. Instead, you may talk to your doctor or nurse over the telephone. You might hear this called self-management.

Problems Emptying Your Bladder

If the cancer is pressing on your urethra or the opening of your bladder, you may find it difficult to empty your bladder fully. This can sometimes cause urine retention, where urine is left in your bladder when you urinate. There are several things that can help, including the following.

Where does uterine cancer spread?

In general, uterine cancer can metastasize to the rectum or bladder. Other areas where it may spread include the vagina, ovaries and fallopian tubes. This form of cancer is typically slow growing and often detected before it has spread to more distant areas of the body.

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What are the symptoms of metastatic uterine cancer?

Pain during sexual intercourse. Unexpected weight loss. Persistent cramping in the pelvic area. Anemia. A physician can run the necessary diagnostic tests to determine if metastatic uterine cancer is the cause of your symptoms.

How to contact Moffitt for metastatic uterine cancer?

If you would like to learn more about receiving diagnostic or treatment services at Moffitt for metastatic uterine cancer, fill out a new patient registration form or call 1-888-663-3488.

Where Bladder Cancer Can Spread

Symptoms and Complications

Treatment Options

Living with Bladder Cancer

Prognosis

Summary

  • Metastatic bladder cancer is cancer that has spread outside of the bladder to other parts of the body. If you have metastatic bladder cancer, your treatment will be focused on destroying or slowing down cancer cells throughout your body, not just in your bladder. There are several treatments for this disease. Chemotherapy is usually the first-line …

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