what chemicals cause bladder cancer

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What are the chances of dying from bladder cancer?

 · Aminobiphenyl, the chemical that exist in the cigarette compound which contribute highly as one of defining aspect on gaining bladder cancer. Benzidine, the common industrial chemicals that exist in the long HM List Of Chemicals Banned In Production as well as a very restricted substance in various areas such as paint, rubber, agriculture, dye production, and the …

What are the risks of bladder cancer?

Some genes control when cells grow, divide into new cells, and die: Genes that help cells grow, divide, and stay alive are called oncogenes. Genes that normally help control cell division, repair mistakes in DNA, or cause cells to die at the right time are called tumor suppressor genes.

What chemicals Cant be detected for cause of death?

Certain industrial chemicals have been linked with bladder cancer. Chemicals called aromatic amines, such as benzidine and beta-naphthylamine, which are sometimes used in the dye industry, can cause bladder cancer. Workers in other industries that use certain organic chemicals also may have a higher risk of bladder cancer.

What is the main cause of bladder cancer?

 · Workplace exposure: Some chemicals used in the dye industry, such as benzidine and beta-naphthylamine, have been associated with bladder cancer. Other industries where chemicals are used that may cause bladder cancer include rubber, leather, textiles, paint manufacturing and printing.

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What are the genes that cause bladder cancer?

Acquired changes in certain genes, such as the TP53 or RB1 tumor suppressor genes and the FGFR and RAS oncogenes , are thought to be important in the development of some bladder cancers. Changes in these and similar genes may also make some bladder cancers more likely to grow and spread into the bladder wall than others.

How do bladder cancer mutations occur?

Some of these acquired gene mutations result from exposure to cancer-causing chemicals or radiation. For example, chemicals in tobacco smoke can be absorbed into the blood, filtered by the kidneys, and end up in urine, where they can affect bladder cells. Other chemicals may reach the bladder the same way. But sometimes, gene changes may just be random events that sometimes happen inside a cell, without having an outside cause.

What are the genes that control cell division?

Some genes control when cells grow, divide into new cells, and die: 1 Genes that help cells grow, divide, and stay alive are called oncogenes. 2 Genes that normally help control cell division, repair mistakes in DNA, or cause cells to die at the right time are called tumor suppressor genes.

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What causes cancer cells to turn on oncogenes?

Cancers can be caused by DNA changes (gene mutations) that turn on oncogenes or turn off tumor suppressor genes. Several different gene changes are usually needed for a cell to become cancer.

Can you get bladder cancer from your parents?

Some people inherit gene changes from their parents that increase their risk of bladder cancer. But bladder cancer does not often run in families, and inherited gene mutations are not thought to be a major cause of this disease.

Why do we look like our parents?

We usually look like our parents because they are the source of our DNA, but DNA affects more than just how we look . Some genes control when cells grow, divide into new cells, and die: Genes that help cells grow, divide, and stay alive are called oncogenes.

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What chemicals can cause bladder cancer?

Certain industrial chemicals have been linked with bladder cancer. Chemicals called aromatic amines, such as benzidine and beta-naphthylamine, which are sometimes used in the dye industry, can cause bladder cancer. Workers in other industries that use certain organic chemicals also may have a higher risk of bladder cancer.

Can cyclophosphamide cause bladder cancer?

Taking the chemotherapy drug cyclophosphamide ( Cytoxan ®) for a long time can irritate the bladder and increase the risk of bladder cancer. People taking this drug are often told to drink plenty of fluids to help protect the bladder from irritation.

What are the risk factors for bladder cancer?

Bladder Cancer Risk Factors. A risk factor is anything that affects your chance of getting a disease such as cancer. Different cancers have different risk factors. You can change some risk factors, like smoking or weight ; others, like your age or family history, you can’t. But having a risk factor, or even many, …

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Why do people with bladder cancer have a higher risk of getting it themselves?

Sometimes this may be because the family members are exposed to the same cancer-causing chemicals (like those in tobacco smoke). They may also share changes in some genes (like GST and NAT) that make it hard for their bodies to break down certain toxins, which can make them more likely to get bladder cancer.

Does pioglitazone cause bladder cancer?

According to the US Food and Drug Administration (FDA), use of the diabetes medicine pioglitazone (Actos ®) is linked with an increased risk of bladder cancer. The risk seems to get higher when higher doses are used.

Does aristolochic acid cause bladder cancer?

The risk seems to get higher when higher doses are used. Dietary supplements containing aristolochic acid ( mainly in herbs from the Aristolochia family) have been linked with an increased risk of urothelial cancers, including bladder cancer.

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Is drinking water a source of arsenic?

For most Americans, drinking water isn’t a major source of arsenic.

Does cyclophosphamide cause bladder cancer?

Treatment with the anti-cancer drug cyclophosphamide increases the risk of bladder cancer. People who received radiation treatments aimed at the pelvis for a previous cancer have a higher risk of developing bladder cancer. Chronic bladder inflammation.

Does smoking cigarettes cause bladder cancer?

Smoking. Smoking cigarettes, cigars or pipes may increase the risk of bladder cancer by causing harmful chemicals to accumulate in the urine. When you smoke, your body processes the chemicals in the smoke and excretes some of them in your urine.

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Where is the bladder located?

Your kidneys, located in the rear portion of your upper abdomen, produce urine by filtering waste and fluid from your blood. Bladder cancer is a common type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in your lower abdomen that stores urine. Bladder cancer most often begins in …

Where does bladder cancer start?

Bladder cancer is a common type of cancer that begins in the cells of the bladder. The bladder is a hollow muscular organ in your lower abdomen that stores urine. Bladder cancer most often begins in the cells (urothelial cells) that line the inside of your bladder. Urothelial cells are also found in your kidneys and the tubes (ureters) …

Where is urothelial cancer found?

Urothelial cells are also found in your kidneys and the tubes (ureters) that connect the kidneys to the bladder. Urothelial cancer can happen in the kidneys and ureters, too, but it’s much more common in the bladder. Most bladder cancers are diagnosed at an early stage, when the cancer is highly treatable.

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Can bladder cancer come back?

But even early-stage bladder cancers can come back after successful treatment. For this reason, people with bladder cancer typically need follow-up tests for years after treatment to look for bladder cancer that recurs.

How do you know if you have bladder cancer?

Bladder cancer signs and symptoms may include: Blood in urine (hematuria), which may cause urine to appear bright red or cola colored, though sometimes the urine appears normal and blood is detected on a lab test. Frequent urination. Painful urination. Back pain.

What chemicals can cause bladder cancer?

Frequent exposure to chemicals that are commonly used in certain jobs may increase bladder cancer risk. This includes chemicals called aromatic amines. They are most commonly used in the textile, dye, rubber, leather, paint, and printing industries. Chemical exposure has also been associated with bladder cancer in truck drivers, hairdressers, and machinists. In addition, areas of the world with high concentrations of arsenic in the groundwater have higher rates of bladder cancer. This includes Chile, Argentina, Taiwan, and some northeastern states of the United States.

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What are the risk factors for bladder cancer?

Bladder cancer can affect anyone. Major risk factors include smoking, exposure to certain chemicals, and having a family history of the disease. Learn more about the risk factors for bladder cancer.

Does smoking cause bladder cancer?

Tobacco use is the biggest risk factor for developing bladder cancer. This risk increases with the amount and length of time smoking. Cancer-causing chemicals inhaled from burning tobacco enter the bloodstream. The body filters them from the blood through the kidneys and transfers them to the bladder to be removed from the body.

Does smoking cigarettes cause cancer?

Cancer-causing chemicals inhaled from burning tobacco enter the bloodstream. The body filters them from the blood through the kidneys and transfers them to the bladder to be removed from the body. The chemical-containing urine can cause damage to the cells in the bladder. Avoiding smoking is the most effective way to lower the risk.

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How does smoking affect the bladder?

The body filters them from the blood through the kidneys and transfers them to the bladder to be removed from the body. The chemical-containing urine can cause damage to the cells in the bladder. Avoiding smoking is the most effective way to lower the risk. People who have quit smoking have a lower risk of bladder cancer compared …

Can you get bladder cancer from a close relative?

You may be twice as likely to develop bladder cancer if you have a close relative who has had the disease. A close relative includes a parent, sibling, or child. This possibility may be related to genetic factors that make it harder for the body to remove dangerous chemicals after exposure.

Can bladder cancer be caused by spinal cord injury?

Long-term bladder irritation and inflammation, such as that caused by infections and bladder or kidney stones, make it more likely for someone to develop bladder cancer. People with spinal cord injuries are at risk of both chronic infections and kidney stones.

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What are the causes of bladder cancer?

While the exact cause of bladder cancer is not known, certain risk factors are linked to the disease, including tobacco smoking and exposure to certain chemicals and gases. Also, people with a family history of bladder cancer have a high risk of developing the disease. Known risk factors for bladder cancer include:

Does cyclophosphamide cause bladder cancer?

Chemotherapy and radiation therapy: Long-term use of the chemotherapy drug cyclophosphamide is associated with an increased risk of bladder cancer. Drinking extra fluids while taking this drug can help lower this risk. Radiation aimed at the pelvis is also considered a risk factor for bladder cancer.

How many people get bladder cancer each year?

Each year, more than 80,000 Americans are diagnosed with bladder cancer. Anyone can get bladder cancer, but factors such as age, race and gender may increase the risk of the disease. Knowing behavior-related risk factors for bladder cancer may help you take preventive measures to reduce your chances of developing the disease or may help you …

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Can anyone get bladder cancer?

Anyone can get bladder cancer, but factors such as age, race and gender may increase the risk of the disease. Knowing behavior-related risk factors for bladder cancer may help you take preventive measures to reduce your chances of developing the disease or may help you and your doctor detect signs of bladder cancer earlier.

Is bladder cancer more common in men or women?

Gender: Men are at a higher risk than women of getting bladder cancer. According to the American Cancer Society, men have an approximately 1 in 26 chance of developing bladder cancer in their lifetime. For women, this chance is about 1 in 86.

How old is the average person with bladder cancer?

Age: Most people who get bladder cancer are older in age. The average age at diagnosis is 73, and 90 percent of patients are over age 55. Race: Bladder cancer is twice as common among Caucasians as African Americans. This disease is less common among Hispanics, Asians and Native Americans.

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Can bladder cancer be genetic?

Other times, they may all have certain genetic abnormalities associated with bladder cancer. Specifically, mutations in genes known as GNT and NAT may trigger changes in the body’s breakdown of some toxins, which may in turn cause cancer cells to form in the bladder wall. Other inherited genetic syndromes are also considered bladder cancer risk …

How do you know if you have bladder cancer?

What Are the Symptoms of Bladder Cancer? 1 Blood in the urine. This is the most common symptom. 2 Having to urinate often. 3 Pain while urinating. 4 Back pain. 5 Pelvic pain.

What is the data visualization tool?

The Data Visualizations tool makes it easy for anyone to explore and use the latest official federal government cancer data from United States Cancer Statistics. It includes the latest cancer data covering the U.S. population.

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Does opium cause bladder cancer?

Opium consumption increases the risk of bladder cancer by 3-fold and concurrent use of opium and smoking increases the risk of bladder cancer by 5 times compared to the general population. Thirty percent of bladder tumors probably result from occupational exposure in the workplace to carcinogens.

Does smoking cigarettes cause bladder cancer?

Smoking (cigar, pipe, Egyptian waterpipe and smokeless tobacco) in any form increases the risk for bladder cancer. Quitting smoking reduces the risk. Risk of bladder cancer decreases by 30% within 1–4 years and continues to decrease by 60% at 25 years after smoking cessation.

What is bladder cancer?

Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder. Symptoms include blood in the urine, pain with urination, and low back pain. It is caused when epithelial cells that line the bladder become malignant.

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What is the treatment for bladder cancer?

Treatment depends on the stage of the cancer. It may include some combination of surgery, radiation therapy, chemotherapy, or immunotherapy. Surgical options may include transurethral resection, partial or complete removal of the bladder, or urinary diversion.

Where is the highest rate of bladder cancer?

In 2018, the highest rate of bladder cancer occurred in Southern and Western Europe followed by North America with rates of 15, 13, and 12 cases per 100,000 people. The highest rates of bladder cancer deaths were seen in Northern Africa and Western Asia followed by Southern Europe.

Is blood in urine a sign of bladder cancer?

Blood in the urine is the most common symptom in bladder cancer, and is painless. Visible blood in the urine may be of only short duration, and a urine test may be required to confirm non-visible blood. Between 80 and 90% of people with bladder cancer initially presented with visible blood.

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Does eating vegetables help with bladder cancer?

As of 2019, there is limited high level evidence to suggest that eating vegetable and fruits decreases the risk of bladder cancer. A 2008 study concluded that “specific fruit and vegetables may act to reduce the risk of bladder cancer.” Fruit and yellow-orange vegetables, particularly carrots and those containing selenium, are probably associated with a moderately reduced risk of bladder cancer. Citrus fruits and cruciferous vegetables were also identified as having a possibly protective effect. However an analysis of 47,909 men in the Health Professionals Follow-Up Study showed little relation between cancer reduction and high consumption of fruits and vegetables overall, or yellow or green leafy vegetables specifically, compared to the reduction seen among those men who consumed large amounts of cruciferous vegetables. An inverse relation between in-takes of flavonols and lignans ( diphenolic compounds found in whole grains, legumes, fruits and vegetables) and aggressive bladder cancer has also been described.

Does trichloroethylene cause cancer?

Prolonged or repeated exposure of trichloroethylene causes kidney cancer. Some evidence suggests that it may be associated with an increased risks of non-Hodgkin lymphoma and, possibly, liver cancer.

Can TCE cause kidney cancer?

Trichloroethylene (TCE) Trichloroethylene, which can cause kidney cancer, was originally developed as an anesthetic. Credit: Science Museum Group, CC BY-NC-SA.

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Where is TCE found?

TCE may be found in the air, water, and soil at places where it is produced or used. It breaks down slowly and remains in the environment for a long time. It readily passes through soil and can accumulate in groundwater.

What is TCE used for?

It is used primarily to make refrigerants and other hydrofluorocarbons and as a degreasing solvent for metal equipment. TCE is also used in some household products, such as cleaning wipes, aerosol cleaning products, tool cleaners, paint removers, spray adhesives, and carpet cleaners and spot removers.

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