when bladder cancer spreads

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How quickly does bladder cancer grow and spread?

 · When cancer cells spread, it’s called metastasis. Cancer is always named for the place where it starts. So when bladder cancer spreads to the bone (or any other place), it’s still called bladder cancer. It’s not called bone cancer unless it starts in the bone. The bladder The bladder is a hollow organ that stores urine before it leaves your body.

How dangerous is bladder cancer?

Bladder cancer spreads when cancerous cells reproduce and invade surrounding healthy tissues. This is known as metastasis. Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well.

What are the early warning signs of bladder cancer?

Bladder cancer can spread through the tissue to nearby organs, such as the prostate (men) or vagina (women). It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body.

What are the stages of bladder cancer?

Chemo (with or without radiation) is typically the first treatment when bladder cancer has spread to distant parts of the body (M1). After this treatment the cancer is rechecked. If it looks like it’s gone, a boost of radiation to the bladder may be given or cystectomy might be done.

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What are the symptoms of end stage bladder cancer?

Symptoms of Advanced Bladder CancerAn inability to urinate.Lower back pain on one side of the body.Loss of appetite.Unintended weight loss.Overwhelming fatigue.Bone pain.Swelling in the feet.

How long does it take bladder cancer to metastasize?

As many as 50% of patients with muscle-invasive bladder cancer may have occult metastases that become clinically apparent within 5 years of initial diagnosis and around 5% will have distant metastasis at the time of initial diagnosis. Most patients with overt metastatic disease die within 2 years despite chemotherapy.

Where does bladder cancer first spread to?

When bladder cancer spreads, it first invades the bladder wall, which is made up of four distinct layers. It can take some time for cancer to penetrate all of these layers, but once it has, it can then spread into the surrounding fatty tissues and lymph nodes.

What happens if bladder cancer has spread?

Bladder cancer gets worse when it grows into or through other layers of the bladder wall. Over time, the cancer may grow outside the bladder into tissues close by. Bladder cancer may spread to lymph nodes nearby and farther away. The cancer may reach the bones, the lungs, or the liver and other parts of the body.

How long can you live with metastatic bladder cancer?

Patients who present with metastatic bladder cancer generally have a poor prognosis, surviving only very few months (1). However, some patients may live considerably longer. If a patient is able to withstand palliative chemotherapy, their remaining lifetime may be extended with systemic treatments.

How do you know when cancer has metastasized?

Some common signs of metastatic cancer include:pain and fractures, when cancer has spread to the bone.headache, seizures, or dizziness, when cancer has spread to the brain.shortness of breath, when cancer has spread to the lung.jaundice or swelling in the belly, when cancer has spread to the liver.

Is bladder cancer aggressive?

It has not grown in toward the hollow part of the bladder, and it has not spread to the thick layer of muscle or connective tissue of the bladder (Tis, N0, M0). This is always a high-grade cancer (see “Grades,” below) and is considered an aggressive disease because it can lead to muscle-invasive disease.

What size bladder tumor is considered large?

First, there is no common agreement regarding what size a bladder tumor constitutes a “large tumor.” In the literature, a large tumor has been variously defined as one with a total resected weight > 50 g, a weight ≥15 g, and a diameter > 5 cm [2-4].

What is life expectancy with bladder cancer?

Survival rates can give you an idea of what percentage of people with the same type and stage of cancer are still alive a certain amount of time (usually 5 years) after they were diagnosed….5-year relative survival rates for bladder cancer.SEER Stage5-year Relative Survival RateDistant6%All SEER stages combined77%2 more rows•Mar 1, 2022

How long can an 80 year old live with bladder cancer?

The authors found an overall 4-year survival rate of 14% for those with a KPS below 80%, compared with 33% for those with a KPS above 80%. Median survival for the entire cohort was 22 months.

Does bladder cancer spread to the brain?

Bladder cancer is known to metastasize to multiple sites of the body but rarely to the brain. When it does metastasize to the brain the prognosis is poor with median survival of 2-4 months despite treatment [8,9].

How long can you live with muscle invasive bladder cancer?

Median overall survival was 12 months. These results may assist in counseling older patients with MIBC if the disease is left untreated.

Can you have bladder cancer for years and not know it?

It may be seen as a symptom of post-menopausal bleeding, simple cystitis or a urinary tract infection. As a result, a bladder cancer diagnosis can be overlooked for a year or more.

Can non invasive bladder cancer metastasis?

Low-grade noninvasive bladder cancer rarely turns into aggressive, invasive, or metastatic disease, but patients are at risk for developing more low-grade cancers throughout their life.

What causes metastatic bladder cancer?

While the exact cause of bladder cancer is not known, certain risk factors are linked to the disease, including tobacco smoking and exposure to certain chemicals and gases. Also, people with a family history of bladder cancer have a high risk of developing the disease.

How long can you live with stage 3 bladder cancer?

Stage 3. Around 40 out of 100 people (around 40%) survive their cancer for 5 years or more after they are diagnosed. Stage 3 means that the cancer has grown through the muscle into the fat layer. It may have spread outside the bladder to the prostate, womb or vagina.

How Does The Doctor Know I Have Bladder Cancer?

Bladder cancer might cause symptoms such as: 1. Having trouble peeing 2. Feeling pain when peeing 3. Needing to go more often than normal 4. Seeing…

Tests to Look For Bladder Cancer

Your doctor may do other tests to find out more about the cancer. Some of them are:X-ray: Dye is put into a vein for a special x-ray of the kidneys…

How Serious Is My Cancer?

If you have bladder cancer, the doctor will want to find out how far it has spread. This is called staging. Your doctor will want to find out the s…

What Kind of Treatment Will I Need?

There’s more than one way to treat bladder cancer. You might want to get a second opinion about the best treatment plan for you. Doctors may have d…

What Will Happen After Treatment?

You will be glad when treatment is over. But it’s hard not to worry about cancer coming back. Even when cancer never comes back, people still worry…

Treating Stage 0 Bladder Cancer

Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis). In either case, the cancer has not inv…

Treating Stage I Bladder Cancer

Stage I bladder cancers have grown into the connective tissue layer of the bladder wall but have not reached the muscle layer.Transurethral resecti…

Treating Stage II Bladder Cancer

These cancers have invaded the muscle layer of the bladder wall. Transurethral resection (TURBT) is typically the first treatment for these cancers…

Treating Stage III Bladder Cancer

These cancers have reached the outside of the bladder and might have grown into nearby tissues or organs.Transurethral resection (TURBT) is typical…

Treating Stage IV Bladder Cancer

These cancers have reached the abdominal or pelvic wall (T4b tumors) or have spread to nearby lymph nodes or distant parts of the body. Stage IV ca…

Treating Bladder Cancer That Progresses Or Recurs

If cancer continues to grow during treatment (progresses) or comes back (recurs), your treatment options will depend on where and how much the canc…

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How does bladder cancer spread?

Bladder cancer spreads when cancerous cells reproduce and invade surrounding healthy tissues. This is known as metastasis. Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well.

Can bladder cancer spread to other organs?

Metastatic bladder cancer can also spread to other organs in the urinary and reproductive tracts, such as the prostate, uterus and vagina.

Where does bladder cancer metastasize?

Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well.

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Where does bladder cancer occur?

Usually, metastatic bladder cancer refers to cancer that has spread to distant organs, but metastasis can occur locally in the muscles and connective tissues that are directly adjacent to the bladder as well.

Is bladder cancer a secondary tumor?

It’s important to remember that when bladder cancer spreads, the secondary tumors are still considered to be bladder cancer – not lung cancer, liver cancer or any other type of malignancy.

What is the treatment for bladder cancer?

Potential treatment options may include chemotherapy, radiation therapy and clinical trials.

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How does bladder cancer spread?

It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body. It can also spread through the body’s blood vessels and form tumors in other parts of the body, …

What is it called when bladder cancer spreads?

1,2 Bladder cancer that has spread ( metastasized) is called metastatic bladder cancer.

What tests determine if bladder cancer has spread?

What Tests Determine Cancer Spread? When a patient is diagnosed with bladder cancer, healthcare providers may carry out further tests to find out if the bladder cancer cells have spread to other organs or parts of the body. 1,2 Bladder cancer that has spread ( metastasized) is called metastatic bladder cancer. …

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How does a tumor spread through the lymph system?

It can also spread through the lymph system, by traveling through lymph vessels to lymph nodes in different parts of the body. It can also spread through the body’s blood vessels and form tumors in other parts of the body, such as the bones or lungs.

Can a retrograde pyelogram detect bladder cancer?

For example, intravenous or retrograde pyelograms are types of x-rays that use a special dye to highlight the organs of the urinary tract. This can make it possible to detect cancer that has spread to the kidneys, ureters, or other parts of the urinary tract. If healthcare providers suspect that the bladder cancer may have spread to …

Can a chest x-ray detect bladder cancer?

If healthcare providers suspect that the bladder cancer may have spread to the patient’s lungs, then a chest x-ray may be used.

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What is a CT scan for bladder cancer?

To check if bladder cancer has spread, CT scans may be used to create images of the entire urinary tract (including the kidneys) as well as lymph nodes, other organs in the abdomen, and the lungs.

How does bladder cancer affect survival?

The factors influencing survival include: 1 Age: Increasing age has been linked to a lower survival rate in people with bladder cancer. 7 2 Sex: A literature review of 27 studies and 23,754 patients found that women had a greater risk for disease recurrence following localized treatment of non-muscle-invasive bladder cancer. 8 3 Smoking: Smoking increases the risk of recurrence and mortality in people with bladder cancer. 9 4 Recurrence: Recurrence of bladder cancer forebodes a poor prognosis, with a median survival of six months after recurrence. Although people with local recurrence have a slightly better prognosis, those with disease recurrence at local and distant sites perform very poorly.

What type of cancer is in the bladder?

The two most common types of cancer affecting the bladder are: Transitional cell carcinoma (TCC): Transitional cell carcinoma of the bladder starts in the bladder. In a study of 33,761 patients in Norway, transitional cell carcinoma accounted for 95% of bladder cancer cases. 2.

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How long does bladder cancer last?

While bladder cancer is relatively common, the average five-year survival rate is quite high at 76.9%. This rate has improved over the past several years, and a person’s chance of survival is influenced by many factors.

What is the bladder made of?

The bladder is flexible, being made of smooth muscle. It works to collect and then eliminate urine from your body. The bladder’s flexible walls are made perfectly to expand and contract as necessary to hold urine until it is expelled from the body. FatCamera / Getty Images.

What is the difference between regional and distant cancer?

Regional means the cancer has spread to nearby lymph nodes or organs and tissues, while distant refers to cancer that has metastasized to distant organs or lymph nodes. The earlier the cancer is found, the higher the chances of survival.

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What is the survival rate for bladder cancer?

For bladder cancer, the five-year relative survival rate when the cancer is at the localized stage is 69.2%. 1. Five-Year Survival Rates by Stage for Bladder Cancer. Stage.

What is the prognosis of bladder cancer?

Prognosis describes how severe a person’s cancer is and their chances of survival. It is influenced by factors that are not reflected in the SEER survival statistics. Chief among them are the type, stage, and grade of bladder cancer. Other factors also contribute.

What is the first treatment for bladder cancer?

Chemo (with or without radiation) is typically the first treatment when bladder cancer has spread to distant parts of the body (M1). After this treatment the cancer is rechecked. If it looks like it’s gone, a boost of radiation to the bladder may be given or cystectomy might be done.

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Can bladder cancer be cured?

The outlook for people with stage 0a (non-invasive papillary) bladder cancer is very good. These cancers can be cured with treatment. During long-term follow-up care, more superficial cancers are often found in the bladder or in other parts of the urinary system.

What are the factors that affect cancer treatment?

Other factors, such as the size of the tumor, how fast the cancer cells are growing (grade), and a person’s overall health and preferences, also affect treatment options.

What is stage 0 bladder cancer?

Stage 0 bladder cancer includes non-invasive papillary carcinoma (Ta) and flat non-invasive carcinoma (Tis or carcinoma in situ). In either case, the cancer is only in the inner lining layer of the bladder. It has not invaded (spread deeper into) the bladder wall.

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Can you get a partial cystectomy for bladder cancer?

Lymph nodes near the bladder are often removed as well. If cancer is in only one part of the bladder, a partial cystectomy may be done instead. But this is possible in only a small number of patients . Radical cystectomy may be the only treatment for people who are not well enough to get chemo.

Is stage IV bladder cancer hard to treat?

These cancers have reached the pelvic or abdominal wall (T4b), may have spread to nearby lymph nodes (any N), and/or have spread to distant parts of the body (M1). Stage IV cancers are very hard to get rid of completely.

Can stage IV cancer spread to lymph nodes?

These cancers have reached the pelvic or abdominal wall (T4b), may have spread to nearby lymph nodes (any N), and/or have spread to distant parts of the body (M1). Stage IV cancers are very hard to get rid of completely.

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What is bladder cancer?

Bladder cancer is any of several types of cancer arising from the tissues of the urinary bladder. Symptoms include blood in the urine, pain with urination, and low back pain. It is caused when epithelial cells that line the bladder become malignant.

Where is the highest rate of bladder cancer?

In 2018, the highest rate of bladder cancer occurred in Southern and Western Europe followed by North America with rates of 15, 13, and 12 cases per 100,000 people. The highest rates of bladder cancer deaths were seen in Northern Africa and Western Asia followed by Southern Europe.

What is the treatment for bladder cancer?

Treatment depends on the stage of the cancer. It may include some combination of surgery, radiation therapy, chemotherapy, or immunotherapy. Surgical options may include transurethral resection, partial or complete removal of the bladder, or urinary diversion.

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What is the survival rate for a bladder transplant?

The typical five-year survival rates in the United States is 77%, Canada is 75%, and Europe is 68%.

Is blood in urine a sign of bladder cancer?

Blood in the urine is the most common symptom in bladder cancer, and is painless. Visible blood in the urine may be of only short duration, and a urine test may be required to confirm non-visible blood. Between 80 and 90% of people with bladder cancer initially presented with visible blood.

Can bladder cancer cause cystitis?

These signs and symptoms are not specific to bladder cancer, and may also be caused by non-cancerous conditions, including prostate infections, overactive bladder or cystitis. Some rare forms of bladder cancer like urachal adenocarcinoma produce mucin, which is then excreted in the urine causing it to be thick.

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Does smoking cause bladder cancer?

Tobacco smoking is the main known contributor to urinary bladder cancer; in most populations, smoking is associated with over half of bladder cancer cases in men and one-third of cases among women, however these proportions have reduced over recent years since there are fewer smokers in Europe and North America. There is an almost linear relationship between smoking duration (in years), pack years and bladder cancer risk. A risk plateau at smoking about 15 cigarettes a day can be observed (meaning that those who smoke 15 cigarettes a day are approximately at the same risk as those smoking 30 cigarettes a day). Smoking (cigar, pipe, Egyptian waterpipe and smokeless tobacco) in any form increases the risk for bladder cancer. Quitting smoking reduces the risk. Risk of bladder cancer decreases by 30% within 1–4 years and continues to decrease by 60% at 25 years after smoking cessation. However, former smokers will most likely always be at a higher risk of bladder cancer compared to people who have never smoked. Passive smoking also appear to be a risk.

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About this Community

The Bladder Cancer Advocacy Network Support Community connects patients, families, friends and caregivers for support and inspiration. This community is sponsored by the Bladder Cancer Advocacy Network, an Inspire trusted partner.

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